We report polymer capsule-based probes for quantifying the pressure exerted by cells during capsule internalisation (Pin). Poly(methacrylic acid) (PMA) capsules with tuneable mechanical properties were fabricated through layer-by-layer assembly. The Pin was quantified by correlating the cell-induced deformation with the ex situ osmotically induced deformation of the polymer capsules. Ultimately...

373 Technology Mapping for FPGAs with Nonuniform Pin Delays and Fast Interconnections Jason Cong, Yean-Yow Hwang and Songjie Xu Department of Computer Science University of California, Los Angeles, CA 90095 fcong, yeanyow, [email protected] Abstract In this paper we study the technology mapping problem for FPGAs with nonuniform pin delays and fast interconnections. We develop the PinMap algorith...

The accuracy and precision of energy dispersive X-ray fluorescence (EDXRF) improve with improved detector energy resolution. However, there are trade-offs between the highest energy resolution and the highest count rates, and there are practical difficulties in achieving the very best energy resolution. Energy resolution differentiates systems but the benefits of improved energy resolution, in ...

The yeast Sup35 and Rnq1 proteins can exist in either the noninfectious soluble forms, [psi-] or [pin-], respectively, or the multiple infectious amyloid-like forms called [PSI+] or [PIN+] prion variants (or prion strains). It was previously shown that [PSI+] and [PIN+] prions enhance one another's de novo appearance. Here we show that specific prion variants of [PSI+] and [PIN+] disrupt each o...

Pin track sepsis is a common complication of circular external fixation. HIV status has been implicated as an independent risk factor for the development of pin track infection and has been cited as a reason not to attempt complex limb reconstruction in HIV-positive patients. This retrospective review of patients treated with circular external fixators looked at the incidence of pin track sepsi...

In this paper, we present a genetic algorithm (GA) for optimization of a multi-mode resource constrained time cost trade off (MRCTCT) problem. The proposed GA, each activity has several operational modes and each mode identifies a possible executive time and cost of the activity. Beyond earlier studies on time-cost trade-off problem, in MRCTCT problem, resource requirements of each execution mo...

BACKGROUND Several studies have examined the biomechanical stability of smooth wire fixation constructs used to stabilize pediatric supracondylar humerus fractures. An analysis of varying pin size, number, and lateral starting points has not been performed previously. METHODS Twenty synthetic humeri were sectioned in the midolecranon fossa to simulate a supracondylar humerus fracture. Specime...

We show that one can recover the PIN from a standardised RSA-based PIN encryption algorithm from a small number of queries to a ciphertext validity checking oracle. The validity checking oracle required is rather special and we discuss whether such oracles could be obtained in the real world. Our method works using a minor extension to the ideas of Bleichenbacher and Manger, in particular we ob...