The use of active lipophilic substances such as antimicrobials and health-related compounds in the food industry is still a challenge due to their poor water solubility and instability in food formulations. Nano-sized structures such as nanoemulsions of oil-in-water are regarded as useful tools with a great potential in the food sector to incorporate food ingredients. Reducing the size of the a...

The rationale of this study acquaint with improvement of sertraline hydrochloride (STH) solubility, formulation of STH nanoemulsion (NE) for intranasal delivery to achieve rapid onset of action and to omit first pass effect with enhanced bioavailability. STH nanoemulsion (NE) system was formulated consisting of capmul MCM as oil phase, tween 80 as surfactant and propylene glycol as cosurfactant...

Our work aimed to investigate the protective effects of saponin-based nanoemulsions of vitamin A and E against oxidative stress-induced cellular damage in AML-12 cells. Saponin nanoemulsions of vitamin A (SAN) and vitamin E (SEN) were prepared by high-pressure homogenization and characterized in terms of size, zeta potential, and polydispersity index. SEN and SAN protect AML-12 cells against ox...

Abstract Background Microalgae are well-established feedstocks for applications ranging from biofuels to valuable pigments and therapeutic proteins. However, the low biomass productivity using commercially available growth mediums is a roadblock its mass production. This work describes strategy boost algal by an effective CO 2 supplement. Results In present study, novel nanoemulsion-based media...

the aim of this investigation was to design and develop nanoemulsions as novel delivery systems for rapamycin. phase behavior of quaternary systems composed of traicetin (as oil), various surfactants and co-surfactants and water at different surfactant/co-surfactant weight ratios were investigated by the construction of phase diagrams. formulations were taken from the o/w ne region of the phase...

Nanoemulsions possess powerful nano-scale properties that make them attractive for diverse applications such as drug delivery, food supplements, nanoparticle synthesis and pharmaceutical formulation. However, there is little knowledge in nanoemulsion literature about controlling and predicting droplet size. In this article, we propose a scaling relation to predict the dependence of nanoemulsion...

A dispersed nano-system with droplet sizes as small submicrons is called a nanoemulsion. Nanoemulsions are thermodynamically stable, transparent, isotropic liquid mixtures of oil, water, surfactant, and co-surfactant. Nanoemulsion typically has between 20 200 nanometer. The size composition the scattered particles in continuous phase primary distinctions an emulsion This approach intended to al...

Nanoemulsions are submicron sized emulsion that is under extensive investigation as drug carriers for improving the delivery of therapeutic agents. These are by far the most advanced nanoparticle systems for the systemic delivery of active pharmaceutical for controlled drug delivery and targeting. These are the thermodynamically stable isotropic system in which two immiscible liquid (water and ...