The objective of this paper is to present a simple, accurate and very efficient method for the evaluation of the field in the vicinity of GSM antennas of the radio base-station in urban areas. The method is based on the replacement of the antenna panel with a group of discrete source emitters. A geometrical approximation is used for the evaluation of the environment’s influence also. The calcul...

A guanine (G638) within the substrate loop of the VS ribozyme plays a critical role in the cleavage reaction. Replacement by any other nucleotide results in severe impairment of cleavage, yet folding of the substrate is not perturbed, and the variant substrates bind the ribozyme with similar affinity, acting as competitive inhibitors. Functional group substitution shows that the imino proton on...

Advances in imaging and endoscopic techniques have improved the ability to diagnose, localize, and treat in a less morbid fashion CSF leaks of the anterior skull base. An appreciation for the mechanism of leak and of the relationship between CSF production and absorption must be kept in mind when individualizing a repair. Increased CSF pressure caused by overproduction or underabsorption may re...

A drainage basin simulation model introduced here incorporates creep and threshold slumping and both detachmentand transport-limited fluvial processes. Fluvial erosion of natural slopes and headwater channels is argued to be dominantly detachment-limited. Such slopes undergo nearly parallel retreat and replacement with alluvial surfaces under fixed base level, in contrast with gradual slope dec...

Among the different base excision repair pathways known, the long patch base excision repair of apurinic/apyrimidinic sites is an important mechanism that requires proliferating cell nuclear antigen. We have reconstituted this pathway using purified human proteins. Our data indicated that efficient repair is dependent on six components including AP endonuclease, replication factor C, proliferat...

Trypanosomatids contain an unusual DNA base J (beta-d-glucosylhydroxymethyluracil), which replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function of base J, we have searched for enzymes that catalyze J biosynthesis. We present evidence that a protein that binds to J in DNA, the J-binding protein 1 (JBP1), may also catalyze the first step in J biosynthesis, t...

We developed a simple and rapid method for constructing knockout vectors using inverse-PCR (IPCR). The method consists of three steps: (i) digestion of a target bacterial artificial chromosome with several restriction enzymes (six-base cutters) followed by self-ligation; (ii) IPCR using circular DNAs as templates and two primers which are oriented in opposite directions; and (iii) cloning into ...

Using ensemble methods is one of the general strategies to improve the accuracy of classifier and predictor. Bagging is one of the suitable ensemble learning methods. Ensemble learning is a simple, useful and effective metaclassification methodology that combines the predictions from multiple base classifiers (or learners). In this paper we show a comparative study of different classifiers (Dec...

The oil-producing fungus Mortierella alpina 1S-4 is an industrial strain. In order to prepare host strains for a transformation system for this fungus, six uracil auxotrophs were obtained by means of random mutation with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). When the activities of orotate phosphoribosyl transferase (OPRTase, EC 2.4.2.10) and orotidine-5'-phosphate decarboxylase (OMPdecas...

— This paper presents a new cache replacement policy based on Instruction-based Reuse Distance Prediction (IbRDP) Replacement Policy originally proposed by Keramidas, Petoumenos, and Kaxiras [5] and further optimized by Petoumenos et al. [6]. In these works [5,6] we have proven that there is a strong correlation between the temporal characteristics of the cache blocks and the access patterns of...