The 15th century cross-vaults of the medieval Modena Cathedral (UNESCO site) consist intricate patches different masonry portions bound by three types lime mortars and at least two gypsum mortars. Such anomalous structure suggests multiple repair works over time after damaging earthquakes.The absolute dating (14C) bricks (TL) integrated with pollen record allowed to clarify construction restora...

At High Energy Physics experiments, extensive parallelism allows scalable, high-bandwidth data acquisition systems. On-line event building of physical events is only feasible by using switch-based event builders. The Barrel Shifter is a well-known event building method for switch-based event builders. Two nondeterministic versions of the Barrel Shifter introduced in this paper provide cost-effe...

The 20th annual Barrels meeting brought together researchers who utilize behavioral, physiological, anatomical, and molecular techniques to understand the structure and function of the barrel system. Barrels XX featured talks on the role inhibition has in shaping cortical responses within the barrel system, the molecular cues that influence the development of the whisker-to-barrel system, and t...

Whole-cell voltage recordings were made in vivo from subsequently reconstructed pyramidal neurons (n = 30) in layer 3 (L3) and layer 2 (L2) of the barrel cortex of urethane-anaesthetised rats. Average resting membrane potentials were well below (15-40 mV) action potential (AP) initiation threshold. The average spontaneous AP activity (0.068 +/- 0.22 APs s-1) was low. Principal whisker (PW) defl...

Resistance to cytotoxic drugs remains a major obstacle for the successful treatment of cancer (1). Over the past two decades, a great deal of information has emerged that elucidates how cancer cells become drug resistant. At least one prominent drugresistance mechanism in cancer cells is the reduction of intracellular drug concentration at the putative drug target. There are at least two mechan...