The interaction of the chemical carcinogen benzo[a]pyrene (BaP) with phosphatidylcholine membranes has been investigated by using various physical techniques. Differential scanning calorimetry showed that BaP, at concentrations as low as 2 mol% in mixtures with dimyristoylphosphatidylcholine (DMPC), dipalmitoylphosphatidylcholine, and distearoylphosphatidylcholine, abolished the pretransition a...

A metric compact space M is seen as the closure of the union of a sequence (Mn) of finite n-dense subsets. Extending to M (up to a vanishing uniform distance) Banach-space valued Lipschitz functions defined on Mn, or defining linear continuous near-extension operators for real-valued Lipschitz functions on Mn, uniformly on n is shown to be equivalent to the bounded approximation property for th...

Staphylococcus aureus is one of the most common root causes of nosocomial infections because of its dominant biofilm forming property. Staphylococci infection is common in both humans and animals. Biofilms have been implicated in almost 60% of all bacterial infections [1]. The bacterial biofilm formation is governed by several factors that are under the control of diverse genetic elements [2]. ...

Abstract Phyto-hormones play a key role in regulating plant responses to stress. Cytokines are type of phyto-hormones involved the regulation many important biological processes related growth, development, and response environmental variables. The exogenous application cytokines increases possibility delaying senescence; however, this is physiological process, and, under certain conditions, de...

We employed the suppressive subtractive hybridization to identify 41 up- and downregulated transcripts in Jurkat cells after benzo[a]pyrene (BaP) treatment. Among the 21 downregulated transcripts, we found that BaP suppresses the Keap1 transcript by 7.5-fold. Subsequent analyses revealed that BaP significantly suppresses the Keap1 message and protein levels to about 40 and 60%, respectively, of...

Particulate matter with an aerodynamic diameter less than 2.5μM (PM2.5) is one of the major environmental pollutants in China. In this study, we carried out a metabolomics profile study on PM2.5-induced inflammation. PM2.5 from Beijing, China, was collected and given to rats through intra-tracheal instillation in vivo. Acute pulmonary injury were observed by pulmonary function assessment and H....

INTRODUCTION One possible mechanism for the postulated link between high consumption of meat and colorectal cancer (CRC) is the content of benzo[a]pyrene (BaP) in meat. METHODS We investigated this association in a population-based case-control study in Western Australia (567 cases and 713 controls). Participants' self-report of meat consumption and lifestyle was used in conjunction with the ...

A wavelength-interrogated surface plasmon resonance (SPR) sensor based on a nanoporous gold (NPG) film has been fabricated for the sensitive detection of trace quantities of benzo[a]pyrene (BaP) in water. The large-area uniform NPG film was prepared by a two-step process that includes sputtering deposition of a 60-nm-thick AuAg alloy film on a glass substrate and chemical dealloying of the allo...

The effect of benzo(a)pyrene (BaP) ship emissions in the greater North Sea region is investigated in this study. The carcinogenic BaP which belongs to the group of polycyclic aromatic hydrocarbons (PAHs) occurs mainly particle bound at temperatures prevailing in the mid-latitudes. The BaP concentration and deposition distribution is investigated by means of the Community Multiscale Air Quality ...

Dietary phospholipids (PLs) and their derivatives have proved active in suppression of various health problems and conditions including cancer. In this work we compared the effect of dietary phospholipids from hen egg yolk enriched with N-acyl ether-phosphatidyl ethanolamine (NAEPE) termed bioactive phospholipids (BAP+ preparation) with PLs lacking NAEPE (BAP- preparation) on the growth of tran...