Background: Light can be absorbed by bacterial pigment and affects its growth. Prodigiosin is a red pigment found in various bacterial species. The purpose of this study was to investigate the impacts of light on prodigiosin production, biomass formation, and membrane integrity of Serratia marcescens y2. Results: S. marcescens y2 grew better and produced more intracellular prodigiosin in darkne...

Listeria monocytogenes (LM) causes a life-threatening infectious disease affecting the brain of humans and domestic animals. Unfortunately, no adequate murine models for CNS listeriosis exist. Using intraparenchymal injection, we have established a new murine model for CNS listeriosis. Injection of a small volume of bacterial suspension limits the bacteria to the brain parenchyma with no leakag...

Host defense peptides are key components of the innate immune system, providing multi-facetted responses to invading pathogens. Here, we describe that the peptide GKS26 (GKSRIQRLNILNAKFAFNLYRVLKDQ), corresponding to the A domain of heparin cofactor II (HCII), ameliorates experimental septic shock. The peptide displays antimicrobial effects through direct membrane disruption, also at physiologic...

Daptomycin is a cyclic anionic lipopeptide antibiotic recently approved for the treatment of complicated skin infections (Cubicin). Its function is dependent on calcium (as Ca2+). Circular dichroism spectroscopy indicated that daptomycin experienced two structural transitions: a transition upon interaction of daptomycin with Ca2+, and a further transition upon interaction with Ca2+ and the bact...

the design and application of a fuzzy logic based controller to a leakage current relay waspresented in this paper. a novel approach based on fuzzy logic to form the tripping action of leakagecurrent relay was investigated. in addition to the theoretical aspect of fuzzy logic, detection of a leakagecurrent, measurement of the leakage current, determination of its duration, trip opening of fault...

Prosthodontic treatment using dental implants is one of the solutions for partially and completely edentulous patients. The peri-implant area is colonized by a large variety of oral microbial complexes. Various prosthesis may provide means of mechanical attachment to the microflora; this in turn allows their aggregation and colonization. There exists a relationship between the peri-implant micr...

Neisseria meningitidis is a strict human pathogen that closely interacts with human endothelial cells via type IV pili in vitro. To decipher whether this interaction plays a role in vivo, we set up an experimental model of fulminant meningococcemia in human skin grafted SCID mice using the wild-type strain 2C4.3. Human skin and mouse tissues were sampled 24 hours after bacterial challenge for h...

Peritoneal dialysis is a method of renal function replacement which has series advantages like greater autonomy the patient, but it also disadvantages, leakage, peritonitis and abdominal wall weakness. We present case patient with history therapy managed on peritoneal presents rare complication that required surgical treatment. A pseudocyst enclosing catheter tip dialysis. The pathogenesis form...

The economic and environmental losses due to serious leakage in the urban water supply network have increased the effort to control the water leakage. However, current methods for leakage estimation are inaccurate leading to the development of ineffective leakage controls. Therefore, this study proposes a method based on the blind source separation theory (BSS) to calculate the leakage of water...