The Iraqi currency notes circulating in Mosul city were evaluated for the occurrence of ESBLs and AmpC b-lactamaseproducing bacteria. Four hundred twenty-two Gram-positive negative bacterial isolates with different antimicrobial resistance profiles recovered from 250 samples collected during period April to July 2021, among which 150 (35.5%) multi-drug resistant (MDR). study found that 16.4% 14...

BACKGROUND Resistance to beta-lactams in Haemophilus influenzae is mostly due to the presence of TEM beta-lactamases. beta-Lactamase-negative ampicillin resistance (BLNAR) also occurs as a result of PBP3 modifications. BLNAR strains are particularly common in Japan and France, and strains with combined mechanisms of altered PBP3 and beta-lactamase (BLPACR) are emerging. Although the prevalence ...

background : gram-negative bacteria are the most cause of nosocomial infection especially in burned patients. carbapenem resistant strains can limit seriously the choice of antibiotic therapy. ampc can make resistance to carbapenem and detection of that can be useful for identification of carbapenem resistant. the aim of this study was identification of ampc in most prevalent cause of nosocomia...

Abstract Background Triple-action diazabicyclooctanes, e.g. zidebactam, combine ?-lactamase inhibition, antibacterial activity, and ‘enhancement’ of PBP3-targeted ?-lactams. Objectives To examine the activity cefepime/zidebactam against consecutive ‘problem’ Gram-negative bacteria referred to UK national reference laboratory. Methods MICs were determined by BSAC agar dilution for 1632 Enterobac...

Four novel oxapenem compounds (i.e., AM-112, AM-113, AM-114, and AM-115) were investigated for their beta-lactamase inhibitory activity against a panel of isolated class A, C, and D enzymes, which included expanded-spectrum beta-lactamase enzymes (ESBLs). The oxapenems were potent beta-lactamase inhibitors. Activity varied within the group, with AM-113 and AM-114 proving to be the most active c...

Urinary tract infection (UTI) during pregnancy is often correlated with complications. As the main objective of this study, we investigated prevalence antimicrobial susceptibility, resistance genes, virulence genes and its relationship different phylogenetic groups among Uropathogenic E. coli strains isolated from pregnant women asymptomatic bacteriuria who referred to Hafez hospital, Shiraz, I...