Cloud-based systems and the datacenter computing environment present a series of challenges to system designers for supporting massively concurrent computation on clusters with commodity hardware. The platform software should abstract the unreliable but highly provisioned hardware to provide a highperformance platform for a diversity of concurrent programs processing potentially very large data...

The architecture of the nucleolus in Allium porum and Triticum vulgare meristematic cells has been investigated by means of digestions with various enzymes. After staining with azure B at pH4, plant nucleoli exhibit lighter regions which, under electron microscopy, correspond to the fibrillar zones characterizing these organelles. Evidence is presented indicating that these latter zones contain...

The metachromatic dye, azure B, was analyzed by microspectrophotometry when bound to DNA fibers and DNA in nuclei with condensed and dispersed chromatin. The interaction of DNA and protein was inferred from the amount of metachromasy (increased beta/alpha-peak) of azure B that resulted after specific removal of various protein fractions. Dye bound to DNA-histone fibers and frog liver nuclei fix...

Analytics over the increasing quantity of data stored in the Cloud has become very expensive, particularly due to the pay-as-you-go Cloud computation model. Data scientists typically manually extract samples of increasing data size (progressive samples) using domain-specific sampling strategies for exploratory querying. This provides them with user-control, repeatable semantics, and result prov...

Bullard Laboratories, University of Cambridge, Madingley Road, Cambridge CB3 0EZ, UK Department of Civil Engineering, Imperial College, London SW7 2AZ, UK The Academy of Athens, Athens 10679, Greece Department of Earth Sciences, University of Oxford, Parks Road, Oxford OX1 3PR, UK Department of Earth Science and Engineering, Imperial College, London SW7 2AZ, UK Oxford Radiocarbon Accelerator Un...

Imagine you are standing in an art museum, mesmerized by an enormous canvas of turbulent paint. Though you find no recognizable images, you are fascinated by the swirling movements of rich azures and cobalt blues. Your eyes follow the artist’s long, energetic brush strokes across the work, and you feel a sense of motion inside your body. Suddenly, your attention is caught by a small area of den...

Enterprises are increasingly deploying their applications in the cloud given the cost-saving advantages, and the potential to geo-distribute applications to ensure resilience and better service experience. However, a key unknown is whether it it is feasible to meet the stringent response time requirements of enterprise applications using the cloud. We make several contributions. First, we show ...