BACKGROUND End-stage hypertrophic cardiomyopathy (HCM) is complicated by substantial adverse events. However, few studies have focused on electrocardiographic features and their prognostic values in HCM. This study aimed to evaluate the clinical manifestations and prognostic value of electrocardiography in patients with end-stage HCM. METHODS End-stage HCM patients were enrolled from a total ...

OBJECTIVES We sought to establish the role of genetic screening for ryanodine receptor type 2 (RyR2) gene mutations in families with effort-induced polymorphic ventricular arrhythmia (PVA), syncope and juvenile sudden death. BACKGROUND The RyR2 mutations have been associated with PVA, syncope and sudden death in response to physical or emotional stress. METHODS We studied 81 subjects (39 ma...

In 1908, Einthovent published the first example of normal electrocardiographic responses to exercise. In 1928, Feil and Siegel2 observed abnormal downsloping ST depression and T wave inversion in three of four patients experiencing anginal attacks (presumably after climbing stairs to the phy-sician's office; H. Hellerstein, personal communication). In 1932, Goldhammer and Scherf3 associated thi...

The use of dynamic electrocardiogram (ECG) monitoring is regarded as a standard of care during general anesthesia and is strongly encouraged when providing deep sedation. Although significant cardiovascular changes rarely if ever can be attributed to mild or moderate sedation techniques, the American Dental Association recommends ECG monitoring for patients with significant cardiovascular disea...

Over the past decade, significant advances were made in the research, diagnosis, and treatment of cardiovascular diseases. Such progress was in every sphere of cardiology that includes non-invasive, minimally invasive, and invasive technologies. Interpretive electrocardiography, cardiac pacemakers, cardiac stents, and angioplasty are some areas where the progress has been significant. Non-invas...

situation resembling most electrophysiological studies. One other factor in favour of subpectoral automatic cardioverter/defibrillator implantation under local anaesthesia is the reduced complexity of the implant procedure, whereby the procedure-related risk for the patients is reduced, since the complication rate during a pacemaker-like approach of automatic cardioverter/ defibrillator implant...

Before it is possible to assess the significance of any variation in the electrocardiographic tracing, it is necessary to know the appearances of the tracing in healthy subjects. Current practice is to record three standard limb leads, three augmented unipolar limb leads, and upwards of seven chest leads. In this way, minor variations from the normal are likely to be appreciated and more accura...

Interest in clinical fetal electrocardiography dates back to 1906 when Cremer4 published two tracings apparently showing fetal deflections of about 0.5 mm. amplitude superimposed on the maternal electrocardiogram of a nine-months gravid woman. The records were obtained with a string galvanometer electrocardiograph with one lead on the abdomen and one in the vagina. During the next 25 years Foa7...