Capripoxviruses cause economically important diseases in domestic ruminants in regions endemic for these viruses. We report here the complete genome sequence of the KSGP 0240 vaccine strain from the live attenuated vaccine Kenyavac (JOVAC).

Salmonella enterica serovar Choleraesuis strain C500 is a live vaccine attenuated by chemical methods. Here, we report the complete genome sequence of the strain, which may be helpful for elucidating the attenuation mechanism of the vaccine strain.

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A new recombination system for the production of live attenuated influenza-A vaccine strains is described. The attenuated parent is the Japanese strain A/Okuda/ 57 (H2N2) which has a known passage history and a good record of human safety. This virus has been recombined with two recent field isolates, A/England/ 42/72 and A/Finland/4/74, and in each case several recombinants were isolated and t...

Background: Pasteurella multocida continues to pose a danger to prone farm and wild animals all over the world. Chemotherapeutic treatments are progressively losing their effectiveness, last for long time, and cost a lot of money, as well as being toxic to human consumers. Therefore, clearing the way for immunization as a big-wheel alternative against the economic grain. Yet, the vaccines avail...

UNLABELLED A randomized clinical trial of hepatitis A vaccines (1 or 2 doses of inactivated vaccine [Healive] or 1 dose of live attenuated vaccine [Biovac]) was conducted among adults to evaluate seroprotection rates and geometric mean concentrations of antibody against hepatitis A virus for 36 months. High rates of seroprotection persisted for at least 36 months among adults who received 1 or ...

OBJECTIVE To determine the feasibility of using volunteers to assist in school-located mass vaccination clinics for influenza. METHODS A set of elementary school-based mass vaccination clinics was implemented in Carroll County, Maryland by the local health department in the 2005-2006 school year. In addition to using health department personnel, fiscal restraints necessitated using medical vo...

California, conducts febrile respiratory illness (FRI) surveillance in civilian and Department of Defense populations at multiple sites across the United States—detecting the first 2 documented cases of a novel, quadruple-reassorted A/H1N1 virus (pH1N1) in California in April 2009 [1]. The NHRC's ongoing febrile respiratory illness surveillance at US military recruit training centers [2] throug...

BACKGROUND The safety, tolerability, and immunogenicity of a monovalent intranasal 2009 A/H1N1 live attenuated influenza vaccine (LAIV) were evaluated in children and adults. METHODS/PRINCIPAL FINDINGS Two randomized, double-blind, placebo-controlled studies were completed in children (2-17 y) and adults (18-49 y). Subjects were assigned 4:1 to receive 2 doses of H1N1 LAIV or placebo 28 days ...

To the editor: We greatly appreciate the editorial by Penttinen and Friede summarising the data regarding recent observations in the United States (US) of decreased effectiveness of the influenza A(H1N1)pdm09 strains (A/California/7/2009 and A/Bolivia/559/2013) included in live attenuated influenza vaccines (LAIV) [1]. Multiple hypotheses have been suggested as potential explanations for the re...