The relationship between heterotopic bone formation and the morphological type of osteoarthritis was examined after 43 hip replacements. Of the 43 hips studied, nine were atrophic, 19 were normotrophic, and 15 were hypertrophic. The incidence of heterotopic bone formation in the atrophic type was 11%, in the normotrophic type 32%, and in the hypertrophic type 87%. The difference between each ty...

Fractional erbium (Er:YAG) and carbon dioxide (CO2) lasers are ablative fractional resurfacing systems widely used to improve the appearance of wrinkles and atrophic scars. However, there have been limited studies comparing the clinical outcome and adverse effects of these two lasers. We conducted a prospective, randomized trial to compare the efficacy and safety of fractional erbium and carbon...

Particular alleles of the interleukin-1B (IL-1B) gene have been correlated with increased risk of atrophic gastritis and gastric cancer in the populations of East Asia and Europe. No such data exist from Peru, a developing country with a population genotypically different from others studied and with a high prevalence of Helicobacter pylori infection and gastric cancer. We conducted a case-cont...

Fracture non-union or delayed union frequently occur after high-energy traumas associated to significant bony tissue loss, in open fractures with infections, and after an inappropriate use of internal fixation.1,2,3,4,5,6,7 Obesity, smoking, abuse of alcohol or drugs, osteoporosis and immunodepression are additional factors that prevent bone healing.1,4,6 Based on characteristic of the bone end...

The sequence of events in the gastric mucosa that precede the manifestation of gastric cancer has been shown to begin decades earlier. Typically, it begins with chronic non-atrophic gastritis that progresses to chronic atrophic gastritis, which may eventually lead to intestinal metaplasia, dysplasia, and finally adenocarcinoma (Kuipers, 1999). Helicobacter pylori infection is accepted as the pr...

This report details surgical procedures for ridge expansion by means of splitting the crest of an edentulous ridge. Atrophic bony ridges present a unique challenge to the dental implant surgeon. In the past, onlay grafts of bone harvested from the hip, maxillary tuberosity, symphysis of the chin, or external oblique ridge have all been used with success in reconstruction of atrophic ridges. How...

background: use of botulinum toxin is becoming a popular way in treatment of some forms of strabismus.to evaluate the morphological changes in the orbital surface layer muscles of the rabbit eye following a single injection of botulinum toxin.   methods: 10 white dutch rabbits weighing 2–3 kg received either 10 units (group 1; n=5) or 20 units (group 2; n=5) of botulinum toxin into the superior...

Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, targets the retinal pigment epithelium (RPE), a monolayer of cells at the back of the eye. As AMD progresses, it can develop into two distinct forms of late AMD: "dry," atrophic AMD, characterized by RPE senescence and geographic RPE loss, and "wet," neovascular AMD, characterized by RPE activation with abnor...

We present a case of Stargardt disease in a 66-year-old man. Fundus examination revealed atrophic macula in both eyes. Fundus autofluorescence (FAF) imaging showed clearly defined hypo-autofluorescent lesions corresponding to the atrophic lesion. In addition, numerous hyper-autofluorescent dots corresponding to the retinal flecks were observed around the atrophic area. Near-infrared FAF imaging...

We mapped a new X-linked recessive atrophic macular degeneration locus to Xp21.1-p11.4 and show allelic involvement of the gene RPGR, which normally causes severe peripheral retinal degeneration leading to global blindness. Ten affected males whom we examined had primarily macular atrophy causing progressive loss of visual acuity with minimal peripheral visual impairment. One additional male sh...