The present case is a 5-month-old female with atopic dermatitis who was brought to hospital for growth failure noted upon regular health examination. Laboratory examinations revealed hyponatremia, hyperkalemia, hypoproteinemia, hypogammaglobulinemia, elevated plasma renin activity and hyperaldosteronemia. Immune function was normal. Composition of the exudate collected from the skin lesions of ...

Atopic dermatitis is a common problem affecting up to 10 percent of all children. The mainstays of therapy have been oral antihistamines, topical emollients, topical doxepin, and topical corticosteroids. Side effects associated with higher potency topical corticosteroids have limited their use in children and for facial areas. Tacrolimus (Protopic) is an immunosuppressive agent typically used s...

It has long been observed that the development of asthma, allergic rhinitis and food allergy are frequently preceded by atopic dermatitis, a phenomenon known as the "atopic march". Clinical, genetic and experimental studies have supported the fact that atopic dermatitis could be the initial step of the atopic march, leading to the subsequent development of other atopic diseases. This brief revi...

Atopic dermatitis (AD) is a common inflammatory skin disorder and characterized by abnormalities in both skin barrier structures and alternations of the immune response. Molecular genetics have dramatically changed our vision of the micro-organisms colonizing the human skin and recently well-documented changes in the skin microbiome in atopic dermatitis have become evident. The microbiome shift...

Atopic dermatitis, one of the most common skin disorders in young children, has a prevalence of 10% to 20% in the first decade of life. It is a chronic illness that requires a multifaceted treatment strategy in the setting of limited therapeutic options. Balancing safety concerns with efficacious treatment is of particular importance in the pediatric population. Parents of patients with atopic ...

Pruritus is an essential feature of atopic dermatitis with a high impact on the quality of life. Although the pathophysiology of atopic dermatitis itch is not fully understood, recent studies have demonstrated that a variety of mechanisms contribute to the induction and maintenance of the symptom. For example, an increased number of cutaneous nerve fibers and neuropeptides were identified in at...

338 Early Clinical Differential Diagnosis between Infant Atopic Dermatitis and Seborrheic Eczema Rubens Marcelo Souza Leite, MD, and Adriana Aragao Craveiro Leite, MD. Departamento Medico, Camara dos Deputados, Brasilia, Brazil; Allergy, Instituto Saint Louis, Brasilia, Brazil. Background: Clinical differential diagnosis between atopic dermatitis and seborrheic eczema is sometimes difficult. Ea...

To ascertain whether an aqueous fraction of Perilla frutescens Britton (PfB/af) has advantageous anti-atopic dermatitis activity, we used a 2,4-dinitrofluorobenzene (DNFB)-induced animal model of atopic dermatitis symptoms to investigate the effects of the extract. We performed an ear swelling assay by comparing thickness of the DNFB-induced ear, and measured the numbers of eosinophils as well ...

338 Early Clinical Differential Diagnosis between Infant Atopic Dermatitis and Seborrheic Eczema Rubens Marcelo Souza Leite, MD, and Adriana Aragao Craveiro Leite, MD. Departamento Medico, Camara dos Deputados, Brasilia, Brazil; Allergy, Instituto Saint Louis, Brasilia, Brazil. Background: Clinical differential diagnosis between atopic dermatitis and seborrheic eczema is sometimes difficult. Ea...

338 Early Clinical Differential Diagnosis between Infant Atopic Dermatitis and Seborrheic Eczema Rubens Marcelo Souza Leite, MD, and Adriana Aragao Craveiro Leite, MD. Departamento Medico, Camara dos Deputados, Brasilia, Brazil; Allergy, Instituto Saint Louis, Brasilia, Brazil. Background: Clinical differential diagnosis between atopic dermatitis and seborrheic eczema is sometimes difficult. Ea...