Last year was the 150th anniversary of Paul Broca's landmark case report on speech disorder that paved the way for subsequent studies of cortical localization of higher cognitive functions. However, many complex functions rely on the activity of distributed networks rather than single cortical areas. Hence, it is important to understand how brain regions are linked within large-scale networks a...

Atlas is a suite of programs developed for assembly of genomes by a "combined approach" that uses DNA sequence reads from both BACs and whole-genome shotgun (WGS) libraries. The BAC clones afford advantages of localized assembly with reduced computational load, and provide a robust method for dealing with repeated sequences. Inclusion of WGS sequences facilitates use of different clone insert s...

Xerostomia (dry mouth), resulting from radiation damage to the parotid glands, is one of the most common and distressing side effects of head-and-neck cancer radiotherapy. Recent MRI studies have demonstrated that the volume reduction of parotid glands is an important indicator for radiation damage and xerostomia. In the clinic, parotid-volume evaluation is exclusively based on physicians' manu...

Background Semi-automated segmentation using deformable registration of atlases consisting of presegmented patient images can facilitate the tedious task of delineating structures and organs in patients subjected to radiotherapy planning. However, a generic atlas based on a single patient may not function well enough due to the anatomical variation between patients. Fusion of segmentation propo...

Introduction: To improve anatomical atlases, we tried to create a printable 3D atlas of rabbit's anatomy based on the Anaglyph. Methods: In this study, twenty white rabbits euthanized and dissected. All 3D images were reconstructed by means of "stereo photo maker (SPM®)" software. Results: By this atlas, users can easily understand nomenclature, the topography and, certainly, the transpo...

The easiest example of a symplectic manifold is the standard sym-plectic vector space V := R 2n with coordinates (q 1 ; p 1 ; :::; q n ; p n) and symplectic form ! = n X j=1 dq j ^ dp j : The basic feature of ! is that it is a closed non-degenerate 2-form on R 2n. In particular it gives a natural indentiication of V with its dual V v ! !(v; :): As an auxiliary structure we also use the standard...

We have developed a method for forming vascular atlases using vascular distance maps and a novel vascular model-to-image registration method. Our atlas formation process begins with MR or CT angiogram data from a set of subjects. We extract blood vessels from those data using our tubular object segmentation method. One subject’s vascular network model is then chosen as a template, and its vascu...

Group-wise registration has been proposed recently for consistent registration of all images in the same dataset. Since all images need to be registered simultaneously with lots of deformation parameters to be optimized, the number of images that the current group-wise registration methods can handle is limited due to the capability of CPU and physical memory in a general computer. To overcome ...

What is the current distribution of the salmon? Has the population of the European otter declined? Which alien species have most recently been discovered in Germany? The Biodiversity Atlas gives the answers. Since 2006, the Project Group AG Biodiversity has been developing the Atlas at the Bremen University of Applied Sciences in cooperation between the Fish Ecology Lab and the Institute of Inf...

BACKGROUND Diffusion tensor imaging is a neuroimaging method that quantifies white matter (WM) integrity and brain connectivity based on the diffusion of water in the brain. White matter has been hypothesized to be of great importance in the development of schizophrenia as part of the dysconnectivity model. Childhood-onset schizophrenia (COS), is a rare, severe form of the illness that resemble...