OBJECTIVE Twenty years ago, the groundbreaking discovery that rearranged during transfection (RET) mutations underlie multiple endocrine neoplasia 2 (MEN2) and familial medullary thyroid cancer (FMTC) ushered in the era of personalized medicine. MEN2-associated signs, taking time to manifest, can be subtle. This study sought to clarify to what extent conventional estimates of 1:200 000-500 000 ...

There is no doubt that when potassium iodide (KI) is administered in a timely fashion, much of the potential exposure to radioactive iodine isotopes from an atmospheric release can be safely averted (1–3). The United States of America Food andDrug Administration (FDA) and theWorld Health Organization (WHO), among others, have established guidelines for the use of KI in these settings (4,5). Leg...

OBJECTIVE Previous studies have evaluated the associations of TNF-α, IL-10 gene polymorphisms and susceptibility to pSS, but the results remained controversial. To assess the associations between TNF-α-308, IL-10-1082, -819, -592 polymorphisms and pSS risk, a meta-analysis was conducted. METHOD The available articles were searched in PubMed, EMBASE and MEDLINE. ORs with 95% CIs were calculate...

There is growing interest in hyperbaric oxygen (HBO) as an adjunctive treatment for muscle injuries. This experiment tested the hypothesis that periodic inhalation of HBO hastens the functional recovery and myofiber regeneration of skeletal muscle after myotoxic injury. Injection of the rat extensor digitorum longus (EDL) muscle with bupivacaine hydrochloride causes muscle degeneration. After i...

BACKGROUND Popliteal fossa pseudoaneurysms as a result of trauma are not uncommon. However, spontaneous pseudoaneurysms as a result of non-traumatic rupture of posterior tibial artery (PTA), anterior tibial artery (ATA), or tibioperoneal trunk (TPT) artery segment are extremely rare. We report a case of spontaneous popliteal fossa pseudoaneurysm resulting from spontaneous avulsion of the ATA an...

The Rapid Prototyping Array (RPA) is a toy radio telescope located 30 miles from U. C. Berkeley in Lafayette, CA. It serves primarily as a software development test bed for the Allen Telescope Array (ATA). We have developed a minimally functional prototype of the ATA control system founded on C++, Java, and a CORBA-based distributed architecture. The system controls RPA pointing, electronics, a...

LORD, GEORGE P., GEORGE F. BOND, AND KARL E. SCHAEFER. Breathing under high ambient pressure. J. Appl. Physiol. 21 (6): 1833-1838. 1966.—The acute effect of high ambient pressure on expiratory airflow was studied in healthy adult males in the ambient pressure range from 1.0 to 7.0 atmospheres absolute pressure (Ata) using a hyperbaric chamber. Changes in flow were assessed with the maximum expi...

The main subjects of discussion, held online within the ETA-CRN board invited 16 expert-panelists are shown. The ad hoc emerged ETA-CRN panel of experts (EPE) first congratulated Professor Kloos and the ATA Taskforce for the extensive work on medullary thyroid cancer, and appreciated discussing the ATA guidelines during the ETA-CRN meeting. As it was not possible for all experts to visit the me...

Original Articles haematologica | 2010; 95(10) 1705 ©F err ata S tor ti F ou nd ati on