نتایج جستجو برای: at this sample size
تعداد نتایج: 7863095 فیلتر نتایج به سال:
Two-stage designs are commonly used for Phase II trials. Optimal two-stage designs have the lowest expected sample size for a specific treatment effect, for example, the null value, but can perform poorly if the true treatment effect differs. Here we introduce a design for continuous treatment responses that minimizes the maximum expected sample size across all possible treatment effects. The p...
An approach to sample size planning for multiple regression is presented that emphasizes accuracy in parameter estimation (AIPE). The AIPE approach yields precise estimates of population parameters by providing necessary sample sizes in order for the likely widths of confidence intervals to be sufficiently narrow. One AIPE method yields a sample size such that the expected width of the confiden...
Multiple comparisons are commonly made in epidemiologic and genetic research. How to appropriately adjust for multiple comparisons remains a controversial issue. This note demonstrates, however, that large increases in the number of comparisons has a limited effect on the sample size required to maintain an experimentwise alpha-level. In particular, the relative sample size required increases o...
Background The evaluation of treatments for rare diseases presents a number of challenges for trial practitioners, regulators and policy makers. Small sample sizes mean that ‘standard’ approaches to trial design and analysis may not be appropriate and alternatives such as Bayesian trial designs have been recommended [Lilford et al 1995]. However, little is known about the design and analysis ap...
Using Tukey-Kramer versus the ANOVA F-test as the omnibus test of the Hayter-Fisher procedure for comparing all pairs of normally distributed means, when sample sizes are unequal, is investigated. Simulation results suggest that using Tukey-Kramer leads to as much or more any-pairs power compared to using the F-test for certain patterns of mean differences, and equivalent per-pair and all-pairs...
In clinical trials, the statistical concepts of significance and power are used in the determination of sample size for trials. The trialist must provide an estimate of standard deviation and a hypothetical population difference to be detected. This must be modified to deal with the designs encountered in guideline research. These are cluster randomized trials, because the patients of a single ...
introduction: the purpose of this article was to evaluate the quality of sample size calculation reports in published clinical trials in journal of endodontics and international endodontic journal in years 2000-1 and 2009-10. materials and methods: articles fulfilling the inclusion criteria were collected. the criteria were: publication year, research design, types of control group, reporting s...
abstract this paper discusses several commonly used models for strategic marketing¹ including market environmental analysis methods (i.e. swot and pest analysis) and strategic marketing tools and techniques (i.e. boston matrix and shell directional policy matrix)and shows how these models may help a firm to achieve its strategic goals. at first, the main reason for doing this research is de...
بررسی رابطه بین یادگیری سازمانی و توانمندسازی مدیران و معاونین مدارس شهرستان میانه دکتر محمد اورکی1، دکتر هاشم نعمتی، گلسیما عزیزی* استادیار گروه علوم تربیتی ، دانشگاه پیام نور تهران جنوب استادیار گروه علوم تربیتی. ، دانشگاه پیام نور مشهد دانشجوی کارشناسی ارشد مدیریت آموزشی ، دانشگاه پیام نور تهران جنوب [email protected] میانه- دانشگاه پیام نور میانه مدیر آموزشی، 2226062 – 0423، ت...
Studies involving two methods for measuring a continuous response are regularly conducted in health sciences to evaluate agreement of a method with itself and agreement between methods. Notwithstanding their wide usage, the design of such studies, in particular, the sample size determination, has not been addressed in the literature when the goal is the simultaneous evaluation of intra- and int...
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