We used National Swine Survey data collected by the National Animal Health Monitoring System to identify litter and herd factors associated with the risk of diarrhea morbidity and mortality in 4to 14-day-old piglets.A total of 29,843 litters from 708 herds monitored for producer-observed health events were included. The rate of diarrhea among 4to 14day-old pigs was one case per day per 250 pigl...

BACKGROUND The prevalence of underfive diarrhea in Somali Regional State, Ethiopia is one of the highest in the country. This study attempted to examine the multiple factors associated with underfive diarrhea and how they might influence its prevalence in Jigjiga, Somali regional state, Ethiopia. METHODS A community based cross-sectional study was conducted from February 15 to 28, 2015. Multi...

Rotavirus has been considered the main agent of infectious diarrhea especially among younger children. We addressed the prevalence of rotavirus-associated diarrhea and the diversity of circulating electropherotypes by immunochromatography and RNA electrophoresis. Stool samples were taken from 391 children (267 with diarrhea) from the lower socioeconomic stratum who sought treatment in the Hospi...

Diarrhea continues to be a leading cause of death in children <5 years of age, and enterotoxigenic Escherichia coli (ETEC) is the most common bacterial cause of children's diarrhea. Currently, there are no available vaccines against ETEC-associated diarrhea. Whole-cell vaccine candidates have been under development but require further improvements because they provide inadequate protection and ...

Background Trofinetide is a recently approved treatment for Rett syndrome (RTT), rare neurodevelopmental disorder with no previously therapy. The phase 3 LAVENDER trial showed improvements in efficacy measures compared placebo, but diarrhea rates were high trofinetide-treated participants. To manage possible diarrhea, recommendations that can be used by health care providers are needed.Research...