amyloid-β (aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in alzheimer’s disease pathology.uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

The line-cell (or line-seru) conversion is an innovation of assembly system applied widely in the electronics industry. Its essence is tearing out an assembly line and adopting a mini-assembly unit, called seru (or Japanese style assembly cell). In this paper, we develop a multi-objective optimization model to investigate two line-cell conversion performances: the total throughput time (TTPT) a...

This paper presents the scientific concerns and some results of the LiMITE – on the Assembly Line: Innovation, Work and Employment – project. Even considering the vast number of experimented industry production technologies, the classic assembly line has proved to be a structuring element within the frame of mass production, whereas known the difficulty to find practical alternative solutions. ...

Assembly lines are special flow-lines production systems which are typical in the industrial production of high quantity standardized commodities. Assembly line balancing is based on evenly distribution of operations between workstations so that each idle time of the machines was minimal. It is assumed that operation times on the machines and the precedence relationship existing between the ope...

Growing interests from customers in customised products and increasing competitions among peers necessitate companies to configure their manufacturing systems more effectively than ever before. We propose a new assembly line system configuration for companies that need intelligent solutions to satisfy customised demands on time with existing resources. A mixed-model parallel two-sided assembly ...

Balancing assembly lines, a family of optimization problems commonly known as Assembly Line Balancing Problem, is notoriously NP-Hard. They comprise a set of problems of enormous practical interest to manufacturing industry due to the relevant frequency of this type of production paradigm. For this reason, many researchers on Computational Intelligence and Industrial Engineering have been conce...