background non-alcoholic fatty liver disease (nafld) is a common liver disease in the western population and expanding disease in the world. pathological changes in fatty liver are like alcohol liver damage, which can lead to end-stage liver disease. the prevalence of nafld in obese or overweight people is higher than general population, and it seems that people with high body mass index (bmi) ...

background: although several observational and experimental studies have examined the effects of low carbohydrate diets (lcds) on nonalcoholic fatty liver disease (nafld), there are considerable inconsistencies among studies. we summarized the effect of lcds on liver function tests, including intrahepatic lipid content (ihlc), alanine transaminase (alt), aspartate aminotransferases (ast),and ga...

OBJECTIVES The purpose of this study was to assess N-acetyl aspartate changes in the thalamus in patients with osteoarthritis of the hip using proton magnetic resonance spectroscopy. METHODS Nine patients with osteoarthritis of the hip (symptomatic group, nine women; mean age 61.4 years (48 to 78)) and nine healthy volunteers (control group, six men, three women; mean age 30.0 years (26 to 38...

The metabolism of glycerate and aspartate was investigated in perfused rat kidneys. The major pathway active for aspartate metabolism and NH3 production was found to include transamination, and not the purine nucleotide cycle. Pyruvate cycling was identified as a means by which reducing potential is generated in the cytosol for glucose and lactate production from these substrates. Inhibition of...

In addition to its function as an excitatory neurotransmitter, glutamate plays a major role as an osmolyte within the central nervous system (CNS). Accordingly, mechanisms that regulate glutamate release and uptake are of physiological importance not only during conditions in which cell volume remains constant but also when cells are subjected to hypoosmotic stress. In the present study, the ab...