نتایج جستجو برای: ascorbic acid 1

تعداد نتایج: 3293345  

Journal: :The Journal of biological chemistry 1954
J J BURNS E H MOSBACH S SCHULENBERG

It is known that, of all animal species studied, only man, other Primates, and the guinea pig are unable to synthesize ascorbic acid. Results obtained in rats, with radioactive glucose, indicate that ascorbic acid is synthesized by a fairly direct route from glucose (l-3), but no information has been available concerning the rate of synthesis and metabolism of ascorbic acid. Such information wo...

In order to evaluate the effect of various levels of drought stress and foliar-application of ascorbic acid on some growth and biochemical parameters of marigold (Calendula officinalis L), an experiment was conducted with a factorial arrangement based on completely randomized design with three replications in Greenhouse of Bardsir Agricultural Faculty, Shahid Bahonar University in 2014. The exp...

2013
Won Kim Seyeon Bae Hyemin Kim Yejin Kim Jiwon Choi Sun Young Lim Hei Jin Lee Jihyuk Lee Jiyea Choi Mirim Jang Kyoung Eun Lee Sun G. Chung Young-il Hwang Jae Seung Kang Wang Jae Lee

The L-gulono-γ-lactone oxidase gene (Gulo) encodes an essential enzyme in the synthesis of ascorbic acid from glucose. On the basis of previous findings of bone abnormalities in Gulo (-/-) mice under conditions of ascorbic acid insufficiency, we investigated the effect of ascorbic acid insufficiency on factors related to bone metabolism in Gulo (-/-) mice. Four groups of mice were raised for 4 ...

Journal: :The Journal of biological chemistry 1985
M Levine K Morita E Heldman H B Pollard

The effect of ascorbic acid on the conversion of dopamine to norepinephrine was investigated in isolated chromaffin granules from bovine adrenal medulla. Ascorbic acid was shown to double the rate of [3H]norepinephrine formation from [3H]dopamine, despite no demonstrable accumulation of ascorbic acid into chromaffin granules. The enhancement of norepinephrine biosynthesis by ascorbic acid was d...

2007
Won-Sang Hwang Seong-Hoon Park Hyun-Seok Kim Hong-Jun Kang Min-Ju Kim Soo-Jin Oh Jae-Bong Park Jaebong Kim Sung Chan Kim Jae-Yong Lee

Ascorbic acid has been reported to extend replicative life span of human embryonic fibroblast (HEF). Since the detailed molecular mechanism of this phenomenon has not been investigated, we attempted to elucidate. Continuous treatment of HEF cells with ascorbic acid (at 200 microM) from 40 population doubling (PD) increased maximum PD numbers by 18% and lowered SA-beta-gal positive staining, an ...

Journal: :The Journal of Cell Biology 1967
Irwin A. Schafer Lloyd Silverman Julia C. Sullivan William Van B. Robertson

Fibroblasts grown in medium containing less than 1 microg of ascorbic acid per milliliter showed evidence of ascorbic acid deficiency when compared with cells grown in medium containing 50 microg of ascorbic acid per milliliter. This was manifested morphologically by dilated endoplasmic reticulum, a decrease in number, size, and intensity of staining of the mitochondria, by defective intercellu...

Journal: :American journal of physiology. Heart and circulatory physiology 2001
S J Duffy N Gokce M Holbrook L M Hunter E S Biegelsen A Huang J F Keaney J A Vita

Hypertension is associated with low plasma ascorbic acid levels and impaired endothelial function. Recent evidence suggests that increased vascular oxidative stress contributes to the pathophysiology of endothelial dysfunction and hypertension. We recently showed that chronic oral ascorbic acid therapy lowers blood pressure in hypertensive patients. We hypothesized that it would also improve en...

Journal: :Archives of disease in childhood 1974
D Liakakos D G Ikkos P Vlachos K Ntalles C Coulouris

Liakakos, D., Ikkos,. D. G., Vlachos, P., Ntalles, K., and Coulouris, Ch. (1974). Archives of Disease in Childhood, 49, 400. Effect of ascorbic acid on urinary hydroxyproline of children receiving corticosteroids. Oral administration of ascorbic acid, 0 * 5 g every 8 hours for a period of 4 days, had no effect on the urinary hydroxyproline excretion of 7 healthy children aged 8 to 14 years. Whe...

Journal: :Reactions Weekly 2021

Rajabi Dehnavi, Ahmad, Zahedi, Morteza,

A pot experiment was conducted during spring and summer of 2017 at collage of agriculture of Isfahan University of Technology, Esfahan, Iran, in order to evaluate the effects of different concentrations of foliar ascorbic acid application on the response of sorghum (speedfeed cultivar) to salinity. Treatments included two salinity levels (0 and 100 mM NaCl) and five concentrations of ascorbic a...

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