The existing technologies for processing of pyrite cinder require improvement complex extraction non-ferrous, precious metals and iron. novelty the technology used in work cinders is preliminary chemical activation a solution sodium bicarbonate. optimal modes were determined according to temperature, duration, L:S ratio NaHCO3 concentration. It has been established that results changes phase co...

Ingestion of sodium fluoride (NaF, 5 mg/kg/body weight) and/or arsenic trioxide (As2O3, 0.5 mg/kg body weight) for 30 days and possible beneficial effects of calcium phosphate and vitamins C and E supplementation for the next 30 days on some parameters in kidney of adult male mice (Mus musculus) were examined. The combined treatment caused a significant decline in total protein and creatinine a...

Arsenic trioxide, as a single agent, has proven efficacy in inducing molecular remission in patients with acute promyelocytic leukemia (APL). There is limited longterm outcome data with single-agent As 2 O3 in the management of newly diagnosed cases of APL. Between January 1998 to December 2004, 72 newly diagnosed cases of APL were treated with a regimen of single-agent As2O3 at our center. Com...

BACKGROUND Arsenic trioxide (As2O3) is an environmental toxicant as well as an effective anti cancer agent against many types of cancers. It is a promising drug for patients with relapsed acute promyelocytic leukaemia (APL), but its clinical efficacy is burdened by the serious cardiac toxicities. AIM The present study was designed to investigate the toxic mechanism of arsenic in cardiac tissu...

CONTEXT This research aimed at verifying the efficacy of homeopathic treatments by plant-based bioassays, which may be suitable for basic research, because they lack placebo effects and provide large datasets for statistical analyses. OBJECTIVE To evaluate the effects of homeopathic treatments of arsenic trioxide (As2O3) on tobacco plants subjected to tobacco mosaic virus (TMV) inoculation as...

Young chicks exhibited a 61% reduction in weight gain when a corn-soybean meal diet was supplemented with 15 mg/kg Se provided as Na selenite. The same level of Se provided as selenomethionine depressed weight gain by 32%. Supplementing the high selenite diet with isoarsenous (14 mg/kg As) additions of As2O5, As2O3, phenylarsonic acid, phenylarsine oxide and roxarsone ameliorated the Se-induced...

Arsenic is a naturally occurring element found widely in the environment. However, on recent days the level of arsenic in the environment has increased several folds due to its use as pesticide, defoliant, electronics, thermal power plants, wood preservatives and metal industry. Arsenic has been reported as one of the most alarming chemical in the environment [1], present in different forms and...

Parental thiamine 100 mg/d was given. The next day, power of the upper limbs dramatically improved and speech became audible. Over the next 5 days, upper limbs regained full power. As2O3 at 5 mg/d for 28 days as maintenance was given 5 weeks later, with oral thiamine. There was no deterioration in neurology. Lower limb power continuously improved. RBC transketolase during arsenic maintenance wa...

Imatinib mesylate (Gleevec, formerly STI571) is an effective therapy for all stages of chronic myelogenous leukemia (CML). While responses in chronic-phase CML are generally durable, resistance develops in many patients with advanced disease. We evaluated novel antileukemic agents for their potential to overcome resistance in various imatinib-resistant cell lines. Using cell proliferation assay...

Targeting tumor-specific metabolic adaptations is a promising anticancer strategy when tumor defense mechanisms are restrained. Here, we show that redox-modulating drugs including the retinoid N-(4-hydroxyphenyl)retinamide (4HPR), the synthetic triterpenoid bardoxolone (2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl ester), arsenic trioxide (As2O3), and phenylethyl isothiocyanate (PEI...