Background—The Y1102 polymorphism of the cardiac sodium channel (SCN5A) gene has been found in 13% of black Americans. It has been linked to lethal arrhythmias in black families with ventricular tachycardia. The prevalence of the Y1102 polymorphism in a series of sudden death in blacks is unknown. Methods and Results—We investigated the incidence of the Y1102 polymorphism in a series of 289 sud...

common congenital cyanotic heart disease, but it can now be treated with very good long term results. It has been known for many years, however, that patients with surgically treated TF are at risk of sudden cardiac death even many years later, while a large number of these patients exhibit postoperative arrhythmias. What is not entirely clear is the relation between ventricular arrhythmias det...

Recent advances in the treatment of arrhythmias have stemmed from careful observation and monitoring in postoperative intensive care areas and from the renewed interest of physicians in the arrhythmias after myocardial infarction. The basic treatment of arrhythmias is the same whenever they occur. Although a knowledge of the electrophysiological changes leading to arrhythmias (Hoffman and Crane...

This paper presents a novel maximum margin clustering method with immune evolution (IEMMC) for automatic diagnosis of electrocardiogram (ECG) arrhythmias. This diagnostic system consists of signal processing, feature extraction, and the IEMMC algorithm for clustering of ECG arrhythmias. First, raw ECG signal is processed by an adaptive ECG filter based on wavelet transforms, and waveform of the...