Studies of epithelial cancers (i.e., carcinomas) traditionally focused on transformation of the epithelium (i.e., the cancer cells) and how aberrant signaling within the cancer cells modulates the surrounding tissue of origin. In more recent decades, the normal cells, blood vessels, molecules, and extracellular components that surround the tumor cells, collectively known as the "tumor microenvi...

This paper presents our experiences in building a UML-based approach for maintaining software products of a large-scale industrial product family. It enables software architects to define rules and constraints for a product family architecture to be enforced on individual product architectures. The target system of our study was the Nokia ISA platform for a mobile phone product family, a comple...

This study aims to evaluate the 50 duplex dwellings of El Miniawy brothers in M'Sila, using methods analysis environmental strategies order verify their application by architects construction these dwellings. A dwelling was selected undertake an a mixed methodological approach, combining qualitative and quantitative method, some whose were evaluated EnergyPlus software validated situ measuremen...

Published by the IEEE Computer Society 0018-9162/11/$26.00 © 2011 IEEE For many computer architects, the first challenge takes priority. After all, we are used to operating under the protection of well-designed abstractions that permit our architectures to accommodate anything from ideal switches to the least palatable of devices that might be foisted upon us. However, the nanodevices that prev...

This paper presents a novel approach to model-driven development of Digital Library (DL) systems. The overall idea is to allow Digital Library systems designers (e.g. information architects, librarians, domain experts) to easily design such systems by using a visual language. We designed a Domain Specific Visual Language for such a purpose and developed a framework supporting it; this framework...