U-Pb dates on magmatic and detrital zircon from samples in the hinterland of the Taconic orogen place new constraints on the timing and plate tectonic geometry of terrane accretion and magmatic arc activity. The Moretown terrane, a Gondwanan-derived exotic block, extends from the Rowe Schist-Moretown Formation contact in the west to the Bronson Hill arc in the east. Arc-related plutonic and vol...

Feeding is regulated by perception in the hypothalamus, particularly the first-order arcuate nucleus (ARC) neurons, of the body's energy state. However, the cellular device for converting energy states to the activity of critical neurons in ARC is less defined. We here show that Na(+),K(+)-ATPase (NKA) in ARC senses energy states to regulate feeding. Fasting-induced systemic ghrelin rise and gl...

Neuropeptide Y (NPY) plays an important role in pain modulation at different levels in the central nervous system. In the brain, NPY and NPY receptors distribute abundantly in the arcuate nucleus of hypothalamus (ARC), a structure involved in pain processing. The present study was undertaken to investigate the role of NPY in nociceptive modulation in the ARC of intact rats and rats with carrage...

By a white noise approach, we characterized the dynamics of the sympathetic baroreflex system in 11 halothane-anesthetized rats. We measured sympathetic nerve activity (SNA) and systemic arterial pressure (SAP), while carotid sinus baroreceptor pressure (BRP) was altered randomly. We estimated the transfer functions from BRP to SNA (mechanoneural arc), from SNA to SAP (neuromechanical arc), and...

Therapeutic irradiation of the brain is commonly used to treat brain tumors but can induce cognitive impairments that can severely affect quality of life. The underlying mechanisms responsible for radiation-induced cognitive deficits are unknown but likely involve alterations in neuronal activity. To gain some mechanistic insight into how irradiation may affect hippocampal neurons known to be a...

Glucosensing neurons in the hypothalamic arcuate nucleus (ARC) were studied using electrophysiological and immunocytochemical techniques in neonatal male Sprague-Dawley rats. We identified glucose-excited and -inhibited neurons, which increase and decrease, respectively, their action potential frequency (APF) as extracellular glucose levels increase throughout the physiological range. Glucose-i...

BACKGROUND In pain processing, long term synaptic changes play an important role, especially during chronic pain. The immediate early gene Arc/Arg3.1 has been widely implicated in mediating long-term plasticity in telencephalic regions, such as the hippocampus and cortex. Accordingly, Arc/Arg3.1 knockout (KO) mice show a deficit in long-term memory consolidation. Here, we identify expression of...

We study the strong gravitational lensing properties of galaxy clusters obtained from N-body simulations with standard ΛCDM cosmology. We have used the 32 most massive clusters from a simulation at various redshifts and ray-traced through the clusters to investigate the giant arcs statistics. We have found that ∼ 40 − 50% of the clusters that produce giant arcs give multiple arcs, which agrees ...

In this paper we present a new technique for improving the azimuth resolution of ultrasonic range sensors frequently used with mobile robots. This improvement is achieved without a significant increase in the latency, or processing delay, of the system. Our approach decreases the azimuth uncertainty of a sensor reading by eliminating portions of the reading that are contradicted by subsequent r...

Immediate early genes (IEGs) typically are the first genetic responders to a variety of cellular activations. The IEG that encodes activity-regulated cytoskeleton-associated protein (arc/arg3.1) has attracted much interest because its mRNA is transported to and translated near activated synapses. Moreover, arc has been implicated in both long-term potentiation (LTP) and long-term depression (LT...