A dental orthosis, designed to increase the size of the upper airway by advancing the mandible, was used in 68 patients to treat snoring and varying degrees of obstructive sleep apnea. The orthosis increased the posterior airway space, as assessed by lateral cephalograms. Seven months (range 2 to 25) after beginning use, 75 percent of patients were using the orthosis regularly. Snoring, by repo...

BACKGROUND Obstructive sleep apnea (OSA) and hypertension are well-known cardiovascular risk factors. Their control could reduce the burden of heart disease across populations. Several drugs are used to control hypertension, but the only consistently effective treatment of OSA is continuous positive airway pressure. The identification of a drug capable of improving OSA and hypertension simultan...

A compact portable sensing system (PSS) was developed for home monitoring of patients with obstructive sleep apnea treated with nasal continuous positive-airway pressure (CPAP). The system consisted of a solid-state pressure sensor connected with plastic tubing to the side port of the nasal CPAP mask, a power supply, and a strip chart recorder. The device was validated against standard polysomn...

The interaction between the cardiovascular system and the respiratory system is complicated and may be used for the rehabilitation of the carotid artery disease. Periodic breathing is an unusual form of breathing with oscillations in minute ventilations and with repetitive apneas or near apneas. Cheyne-Stokes like breathing during sleep may be associated with obstructive sleep apnea (OSA) in so...

Treatment of obstructive sleep apnea with nasal continuous positive airway pressure mandates simultaneous increases of both inspiratory and expiratory positive airway pressures to eliminate apneas as well as nonapneic oxyhemoglobin desaturation events. We hypothesized that the forces acting to collapse the upper airway during inspiration and expiration are of different magnitudes and that obstr...

Introduction: The development of repetitive central apneas during application of CPAP in patients initially showing obstructive apneas, a condition called complex sleep apnea syndrome (CompSAS), implies respiratory control instability. Respiratory control is known to be transiently destabilized by arousals. We hypothesized that PLMS and PLMrelated arousals would be more frequent in patients wit...

The prevalence of OSAS in children is 0.7-3%, with peak incidence in pre-schoolers. It is characterised by partial or complete upper airway obstruction during sleep, causing intermittent hypoxia. Both anatomical (severe nasal obstruction, craniofacial anomalies, hypertrophy of the pharyngeal lymphoid tissue, laryngeal anomalies, etc.) and functional factors (neuromuscular diseases) predispose t...

W read with interest your editorial entitled “Will Physicians Eventually Become Shift Workers?” Apropos to the ideas mentioned there, we would like to mention the email survey we conducted in 2005 of practicing physicians in our area. An IRB approved questionnaire looking at their sleep habits (total sleep time per night, napping, snoring, observed apneas, chronic illness, medication use, caffe...

Pediatric Obstructive Sleep Apnea is a part of the spectrum Sleep-Disordered Breathing that characterized by frequent arousals, apneas, and hypopneas. It can be associated with reduction in blood oxygen saturation hypoventilation during sleep children. If left untreated or adequately treated, it lead to long-term sequelae involving cardiovascular, endothelial, metabolic, endocrine, neurocogniti...

Patients with the sleep apnea/hypopnea syndrome (SAHS) often have more apneas supine that sitting. We have shown radiologically that although the retropalatal airway narrows on lying down, the retroglossal airway widens. We have thus investigated the effect of posture on genioglossal EMG activity in 10 normal subjects and 10 patients with SAHS (58 +/- 29 SD apneas + hypopneas/h) using peroral i...