Serial episode is a type of temporal frequent pattern in sequence data. In this paper we compare the performance of serial episode discovering algorithms. Many different algorithms have been proposed to discover different types of episodes for different applications. However, it is unclear which algorithm is more efficient for discovering different types of episodes. We compare Minepi and WinMi...

Three distinct adaptor protein (AP) complexes involved in protein trafficking have been identified. AP-1 and AP-2 mediate protein sorting at the trans-Golgi network and plasma membrane, respectively, whereas the function of AP-3 has not been defined. A screen for factors specifically involved in transport of alkaline phosphatase (ALP) from the Golgi to the vacuole/lysosome has identified Ap16p ...

Intracellular protein trafficking pathways are hijacked by viruses at various stages of viral life-cycle. Heterotetrameric adaptor protein complexes (APs) mediate vesicular trafficking at distinct intracellular sites and are essential for maintaining the organellar homeostasis. In the present study, we studied the effect of AP-1 and AP-3 deficiency on flavivirus infection in cells functionally ...

Absolute pitch (AP) perception is the auditory ability to effortlessly recognize the pitch of any given tone without external reference. To study the neural substrates of this rare phenomenon, we developed a novel behavioral test, which excludes memory-based interval recognition and permits quantification of AP proficiency independently of relative pitch cues. AP- and non-AP-possessing musician...

Tyrosyl-DNA phosphodiesterase 1 (Tdp1) catalyzes the hydrolysis of the phosphodiester linkage between the DNA 3' phosphate and a tyrosine residue as well as a variety of other DNA 3' damaged termini. Recently we have shown that Tdp1 can liberate the 3' DNA phosphate termini from apurinic/apyrimidinic (AP) sites. Here, we found that Tdp1 is more active in the cleavage of the AP sites inside bubb...

background: to investigate the association between the red cell distribution width (rdw) and mortality in patients with acute pancreatitis (ap), and to assess the ability of rdw to predict mortality in ap patients. materials and methods: this retrospective cohort study included 120 patients (50 males and 70 females) with ap who were admitted to the first affiliated hospital of zhongshan medical...

introduction: foot insoles are widely recommended to prevent running related to injuries. however, their effects on the frequency of ground reaction force(grf) is still unclear. the purpose of this study was to elemental test the effect of four shoe insoles on frequency of grf during stance phase of running. materials and methods: 15 female students (mean age22±1/85 year, height162±4/71cm and w...