نتایج جستجو برای: antiinflammatory effects

تعداد نتایج: 1547624  

Journal: :Pediatrics 2015
Roger F Soll William O Tarnow-Mordi

There are many potential benefits of delayed or deferred cord clamping (DCC) compared with immediate cord clamping (ICC). Increasing placental transfusion by DCC increases neonatal blood volume and improves transitional hemodynamics. DCC may also increase iron stores, reducing childhood anemia and increasing the transfer of stem cells, which may have antiinflammatory neurotropic and neuroprotec...

Journal: :Pharmacognosy Journal 2021

Peppermint, (Mentha ×piperita), aromatic perennial herb of the mint family (Lamiaceae). It is a natural hybrid Mentha spicata and aquatica found wild with its parent species in central as well southern Europe. holds various types ingredients including menthol, menthone cineol. Menthol, which extracted from peppermint, play an important role inhibition pathogenesis. Peppermint oil also acts mild...

Journal: :Endocrine reviews 2005
Jonathan Rosen Jeffrey N Miner

Steroidal glucocorticoids are commonly used due to their powerful antiinflammatory activity. However, despite their excellent efficacy, severe side effects frequently limit the use of these drugs. The search for novel glucocorticoids with reduced side effects has been intensified by the discovery of new molecular details regarding the function of the glucocorticoid receptor. These new insights ...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2000
R de la Puerta E Martínez-Domínguez V Ruíz-Gutiérrez

Interest in the health-promoting effects of virgin olive oil, an important part of the "Mediterranean diet", prompted us to determine the antiinflammatory effects of erythrodiol, beta-sitosterol and squalene, identified as major components of the so-called "unsaponifiable fraction" of virgin olive oil, as well as of the phenolic compounds from the "polar fraction": oleuropein, tyrosol, hydroxyt...

Journal: :Circulation 2008
Wei-Jian Zhang Karyn E Bird Timothy S McMillen Renee C LeBoeuf Tory M Hagen Balz Frei

BACKGROUND Vascular inflammation and lipid deposition are prominent features of atherosclerotic lesion formation. We have shown previously that the dithiol compound alpha-lipoic acid (LA) exerts antiinflammatory effects by inhibiting tumor necrosis factor-alpha- and lipopolysaccharide-induced endothelial and monocyte activation in vitro and lipopolysaccharide-induced acute inflammatory response...

2016
Nicholas S. Kirkby Abel Tesfai Blerina Ahmetaj-Shala Hime H. Gashaw Walkyria Sampaio Gisele Etelvino Nádia Miricéia Leão Robson A. Santos Jane A. Mitchell

Nonsteroidal antiinflammatory drugs, including ibuprofen, are among the most commonly used medications and produce their antiinflammatory effects by blocking cyclooxygenase (COX)-2. Their use is associated with increased risk of heart attacks caused by blocking COX-2 in the vasculature and/or kidney, with our recent work implicating the endogenous NOS inhibitor asymmetric dimethylarginine (ADMA...

2008
Wei-Jian Zhang Karyn E. Bird Timothy S. McMillen Renee C. LeBoeuf

Background—Vascular inflammation and lipid deposition are prominent features of atherosclerotic lesion formation. We have shown previously that the dithiol compound -lipoic acid (LA) exerts antiinflammatory effects by inhibiting tumor necrosis factor– and lipopolysaccharide-induced endothelial and monocyte activation in vitro and lipopolysaccharide-induced acute inflammatory responses in vivo. ...

Journal: :The Journal of clinical investigation 2011
Christian Besler Kathrin Heinrich Lucia Rohrer Carola Doerries Meliana Riwanto Diana M Shih Angeliki Chroni Keiko Yonekawa Sokrates Stein Nicola Schaefer Maja Mueller Alexander Akhmedov Georgios Daniil Costantina Manes Christian Templin Christophe Wyss Willibald Maier Felix C Tanner Christian M Matter Roberto Corti Clement Furlong Aldons J Lusis Arnold von Eckardstein Alan M Fogelman Thomas F Lüscher Ulf Landmesser

Therapies that raise levels of HDL, which is thought to exert atheroprotective effects via effects on endothelium, are being examined for the treatment or prevention of coronary artery disease (CAD). However, the endothelial effects of HDL are highly heterogeneous, and the impact of HDL of patients with CAD on the activation of endothelial eNOS and eNOS-dependent pathways is unknown. Here we ha...

Journal: :Exercise and sport sciences reviews 2015
Victoria J Vieira-Potter Terese M Zidon Jaume Padilla

Adipose tissue inflammation links obesity and metabolic disease. Both exercise and estrogen improve metabolic health, enhance mitochondrial function, and have antiinflammatory effects. We hypothesize that there is an inverse relationship between mitochondrial function and inflammation in adipose tissue and that exercise acts as an estrogen "mimetic." Explicitly, exercise may improve adipose tis...

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