Cysts of the median raphe are uncommon. We describe a 43-year-old man with an asymptomatic nodule on the glans penis. Excision of the lesion was performed followed by histological and immunohistochemical studies. Histopathological examination revealed a solitary unilocular cystic cavity in the corium, lined by a pseudostratified columnar epithelium, among which mucinous cells where identified. ...

35 Types of T-cell responses are categorized on the basis of a limited number of molecular 36 markers selected using a priori knowledge about T-cell immunobiology. We sought to 37 develop a novel systems-based approach for the creation of an unbiased framework 38 enabling assessment of antigenic-peptide specific T-cell responses in vitro. A meta39 analysis of transcriptome data from PBMCs stimu...

The observation that aspirin inhibits the increment in tissue plasminogen activator ft-PA) activity induced by venous occlusion of the forearm became controversial with the publication of several nonconfirmatory studies. The current study was performed to confirm the original observation and determine the mechanism by which aspirin suppresses the incremental t-PA activity induced by venous occl...

Only two of the epidermal tumors of man unquestionably result from a virus infection— warts and molluseum eontagiosum. Neither of these contains a potent antigen. Antibodies to warts, for instance, have not been demonstrated, and until recently the situation for molluscum contagiosum remained controversial; most workers had failed to find humoral antibodies (1, 2). Only Mitchell (3) observed co...

Abstract Background The giant panda ( Ailuropoda melanoleuca ) is a threatened endemic Chinese species and flagship of national global conservation concern. Life history theory proposes that reproduction immunity can be mutually constraining interrelated. Knowledge changes male pandas during the breeding season limited. Results Here, we researched peripheral blood gene expression profiles assoc...

Rhodococcus equi is an important pathogen in foals; however, its incidence in African indigenous animals is poorly understood. Fecal samples (92 from nine indigenous species) and 43 soil samples were collected from two Zambian National Parks. The presence of R. equi was investigated and 533 isolates were tested for the presence of 15- to 17-kDa antigens (VapA) and a 20-kDa antigen (VapB) by imm...

The production and regulation of interleukin (IL) IL-13, IL-4 and interferon-gamma (IFN-gamma) was evaluated in 43 schistosomiasis patients with different clinical forms. Whole-blood cultures cytokine production in response to soluble egg antigen (SEA), soluble worm adult preparation (SWAP), mitogens, neutralizing antibodies or recombinant IL-13 were measured by ELISA. After SWAP stimulation, c...

It was demonstrated that mycoplasmas, gram-negative bacteria, and certain gram-positive bacteria share a similar protein antigen with a molecular weight ranging from 42,000 to 48,000. Western blotting (immunoblotting) with an antibody specific to a 43-kDa membrane protein of Mycoplasma fermentans showed the existence of this protein antigen in all Mycoplasma spp. tested (14 species), Acholeplas...

PURPOSE AND EXPERIMENTAL DESIGN To detect surgically resectable tumors earlier and improve the prognosis of esophageal squamous cell carcinoma patients, we examined deltaNp63 expression that was specific for squamous cell carcinoma in blood samples obtained from 43 esophageal cancer patients. RESULTS Seventeen of 33 (52%) patients with primary esophageal squamous cell carcinoma and 6 of 10 (6...