Background: Fertility control is an issue of global and national public health concern. Though considerable progress has been made in the development of methods of contraception among females, progress and possibilities are still slow and limited. Therefore, there is a need to develop new contraceptive modalities for males. In this study the antifertility activities of Cornus mas were evaluated...

A single instillation of an aqueous suspension containing 40 mg. of quinacrine hydrochloride into the uterine horns of adult rats prevented implantation for at least 4 weeks. A suboptimal dose of 5 mg. could be potentiated by the addition of epinephrine or metaraminol. In some animals, the use of the quinacrine hydrochloride suspension resulted in atrophy and necrosis of the treated uterine hor...

Plants have served as a natural source of antifertility substances. Henshaw (1953) listed many plants used by primitive people in different countries to control fertility. Though many indigenous plants have been shown to prevent births, only a few plants have so far been investigated for antispermatogenic activity (Kholkute, 1977; Segal, 1985; Rao, 1988; Murugavel and Akbarshah, 1991; Chatterje...

Sperm proteins are known to be associated with normal fertilization as auto- or iso-antibodies to these proteins may cause infertility. Therefore, sperm proteins have been considered to be the potential candidate for the development of antifertility vaccine. Some of the sperm proteins proved to be promising antigens for contraceptive vaccine includes lactate dehydrogenase (LDH-C4), protein hyal...

To date, there is no report on safety of Artemisia Kopetdaghensis. This study aimed to determine the possible undesirable effects of A. Kopetdaghensis on reproduction of female rats. The pregnant rats were treated (i.p.) with vehicle or 200 and 400 mg/kg of A. Kopetdaghensis hydroalcoholic extract from the 2nd to 8th day of pregnancy. Then, number and weight of neonates, duration of pregnancy, ...

Turmeric is used as a condiment and also as a herbal medicine in different kinds of illness. It is used by tribes as an antifertility and aborcifacient agent for a long period in different parts of India. Because of scarcity of research data regarding the effectiveness and mode of action of curcumin, the active principle present in turmeric, we undertake this research work to evaluate its antif...

Moringa concanensis Nimmo. (Moringaceae) is a wild plant found in India. Traditionally, tribes used this as an antioxidant, anticancer, anticonvulsant, antimicrobial, antifertility, anti-inflammatory, antipyretic, and analgesic. In the present study, leaves of were subjected to successive solvent extraction with five different solvents increasing polarity, i.e., petroleum ether, chloroform, eth...