conclusions the emergence of streptococcus pneumoniae strains with multiple resistance needs permanent monitoring of antibiotic susceptibility patterns of clinical isolates. we have found that ceftazidime is not a suitable drug for choosing the treatment of pneumococcal infections. results the study showed that three strains (6%) and six strains (12%) indicated intermediate resistance and compl...

A disposable microarray was developed for detection of up to 90 antibiotic resistance genes in gram-positive bacteria by hybridization. Each antibiotic resistance gene is represented by two specific oligonucleotides chosen from consensus sequences of gene families, except for nine genes for which only one specific oligonucleotide could be developed. A total of 137 oligonucleotides (26 to 33 nuc...

Although DNA encoding antibiotic resistance has been discovered in antibiotic preparations, its significance for the development of antibiotic resistance in bacteria is unknown. No phylogenetic evidence was obtained for recent horizontal transfer of antibiotic resistance genes from antibiotic-producing organisms to bacteria from human or animal sources.

Antibiotics have natural functions, mostly involving cell-to-cell signaling networks. The anthropogenic production of antibiotics, and its release in the microbiosphere results in a disturbance of these networks, antibiotic resistance tending to preserve its integrity. The cost of such adaptation is the emergence and dissemination of antibiotic resistance genes, and of all genetic and cellular ...

Increasing antibiotic resistance genes in the environment may pose a threat to public health. In this study, tetracycline and sulfonamide resistance genes (Tet-W, Tet-O, and Sul-I) were quantified in 24 manure samples from three farms and 18 biosolids samples from seven different wastewater treatment plants using quantitative polymerase chain reaction methods. Concentrations of Tet-W and Tet-O ...

Antibiotic Resistance Pattern and Prevalence of tetA, tetB, tetR, OXA-10 OXA-48 Genes among Escherichia coli Isolates from Toilets in Mashhad Azad University (Iran) 2020

conclusions in the present study, we found a high prevalence of mrsa at the hospitals studied. the findings emphasized the increased prevalence of mrsa isolates containing different toxin and adhesion genes, probably accompanied by antimicrobial resistance. infection with such isolates worsens the clinical outcomes as well as the morbidity and mortality rates in hospitalized patients in icus. m...