starting from readily available 2-substituted-4-methylthiazole-5-carboxylic acid hydrazide (1), the title compounds were prepared. the reaction of compound 1 (r=ch3) with formic acid yielded 1-(formyl)-2-(2,4-dimethylthiazole-5-carboxyl) hydrazine (2). refluxing the latter with phosphorous pentasulfide in xylene afforded compound 3, the reaction of compound 2 with phosphorous pentoxide afforded...

introduction: aloe vera compounds have inhibitory activity on fungi, bacteria, and viruses. this study examines the antibacterial activity of a. vera purified extracts including gel, boiled skin, boiled gel, and distilled extract against pathogenic bacteria, staphylococcus aureus, methicillin-resistant s. aureus (mrsa), klebsiella pneumonia and pseudomonas aeruginosa were elucidated. method: th...

introduction: natural products have been the most successful source of potential drug leads. one of them is lichens, which have been used since antiquity as natural sources of drugs. the aim of this study was to investigate the antibacterial and antifungal activity of different extracts of the iranian lichens in ilam province. methods: the aqueous, acetone, and methanol extracts of 6 lichen spe...

three native turkish medicinal and aromatic plants (artemisia absinthum, artemisia santonicum and saponaria officinalis) were investigated to analyze their antioxidant activity, total phenolic content and antimicrobial activity. their total antioxidant activity was determined by using a β-carotene bleaching assay and their antimicrobial activity was determined by utilizing an agar disc diffusio...

Alpha-melanocyte stimulating hormone (alpha-MSH) is an endogenous anti-inflammatory peptide reported to possess antimicrobial properties, however their role as antibacterial peptides is yet to be established. In the present study, we examined in vitro antibacterial activity of alpha-MSH against S. aureus strain ISP479C and several methicillin-sensitive (MSSA) and methicillin-resistant (MRSA) S....

In response to the wide spread of microbial contamination induced by bacterial pathogens, the development of novel materials with excellent antibacterial activity is of great interest. In this study, novel antibacterial chitosan (CS) and polyhexamethylene guanidine hydrochloride (PHGC) dual-polymer-functionalized graphene oxide (GO) (GO-CS-PHGC) composites were designed and easily fabricated. T...

OBJECTIVE Non-steroidal anti-inflammatory drugs (NSAIDs) have shown antibacterial activity in some recent studies. The aim of this study was to evaluate the antibacterial effect of diclofenac against Enterococcus faecalis (E. faecalis) as a resistant endodontic bacterium in comparison with ibuprofen, calcium hydroxide and amoxicillin. MATERIALS AND METHODS The antibacterial activity of materi...

Background Staphylococcus aureus, methicillin-resistant and Escherichia coli, multidrug-resistant included in the list of antibiotic-resistant priority pathogens from WHO. As multidrug-resistant bacteria problem is increasing, it is necessary to probe new sources for identifying antimicrobial compounds. Medicinal plants represent a rich source of antimicrobial agents. One of the potential plant...

BACKGROUND Anethum graveolens Linn., Foeniculum vulgare Mill. and Trachyspermum ammi L. are widely used traditional medicinal plants to treat various ailments. To provide a scientific basis to traditional uses of these plants, their aqueous and organic seed extracts, as well as isolated phytoconstituents were evaluated for their antibacterial potential. METHODS Antibacterial activity of aqueo...

Three mouthwashes Gengigel, Oradex and Salviathymol N, were tested using experimental microorganisms included Fusobacterium nucleatum, Streptococcus mitis, Streptococcus constellatus, Eikenella corrodens and dental plaque. Staphylococcus aureus and Escherichia coli were used as internal controls. Antibacterial activity was done by diffusion test. Minimum inhibitory concentration test and assess...