BACKGROUND Tuberculosis drug-resistance becomes common in sub-Saharan Africa; however, very few data are available in Burkina Faso. The aim of this study is to assess the acquired resistance of Mycobacterium tuberculosis complex strains identified in TB patients to four first-line drugs in Ouagadougou. METHODS One hundred and ten (110) pulmonary tuberculosis patients with acid-fast bacilli-po...

A cross-sectional descriptive study was carried out at a tuberculosis center, Yangon, Myanmar from October 2003 to July 2004 to analyze the drug susceptibility of new sputum smear positive pulmonary tuberculosis patients. A total of 202 Mycobacterium tuberculosis isolates were tested for resistance to isoniazid, streptomycin, rifampicin and ethambutol. Resistance to at least one anti-tuberculos...

BACKGROUND The tuberculosis and infections caused by nontuberculous mycobacterial (NTM) species are increasing in patients presented with respiratory illness, and it is crucial to document the epidemiology of these infections. OBJECTIVES To study the mycobacterial species and in vitro drug susceptibility trends of Mycobacterium tuberculosis found in the respiratory specimens. MATERIALS AND ...

INTRODUCTION Hepatotoxicity is one of the most frequent adverse events occurring during tuberculosis treatment that may negatively affect treatment compliance, clinical outcome. This study was designed to evaluate management, risk factors related to hepatotoxicity during tuberculosis treatment. PATIENTS AND METHODS Hospitalized patients for tuberculosis treatment at Sureyyapasa Chest Diseases...

Drugs that kill tuberculosis more quickly could shorten chemotherapy significantly. In Escherichia coli, a common mechanism of cell death by bactericidal antibiotics involves the generation of highly reactive hydroxyl radicals via the Fenton reaction. Here we show that vitamin C, a compound known to drive the Fenton reaction, sterilizes cultures of drug-susceptible and drug-resistant Mycobacter...

Pancreatic tuberculosis is a very rare disease in either immunocompetent or immunocompromised hosts.The incidence of pancreatic was reported to be less than 4.7% an autopsy series on patients 1944 and 2% another 1966.Despite that, recent times, increase the number reports TB has been noted.This condition possibly caused by improvement diagnostic imaging tools, development different techniques t...

background early treatment of pulmonary tuberculosis (ptb) is necessary for a successful tuberculosis (tb) control program. objectives the objective of this study was to determine total treatment delay and its associated factors among ptb patients in ahvaz. patients and methods a retrospective study was performed among newly diagnosed ptb cases registered in 2010 at the ahvaz health center. tot...

The objective: to determine possibility of prescribing and safety various anti-tuberculosis drugs their combinations as part a therapeutic or preventive course therapy (ATBT) in patients with end-stage chronic kidney disease (CKD) receiving hemodialysis replacement the settings high prevalence drug resistant strains Mycobacterium tuberculosis. Subjects Methods. 42 were followed-up by Central Tu...

BACKGROUND Fluoroquinolones are considered important substitutes for the treatment of tuberculosis. This study investigates the current status of fluoroquinolone for the treatment of tuberculosis. METHODS In 2009, a retrospective analysis was performed at one tertiary referral center for 953 patients diagnosed with tuberculosis. RESULTS A total of 226 patients (23.6%), who received fluoroqu...

Using a combination of aspirin, anti-tuberculosis drugs and steroids may help to reduce the number of strokes and deaths in patients with tuberculous meningitis.