background: thyroid autoimmunity may be linked to infertility, in both thyrotropin (tsh)-dependent and tsh-independent fashion. the aim of the present study was to assess this presumed reciprocal relationship of thyroid autoimmunity and pregnancy. methods: tsh and antithyroid peroxidase autoantibodies (anti-tpo) were evaluated retrospectively over an eight-year period in 444 greek women who had...

Clinical consequences of subclinical hypothyroidism (SH) are still controversial, especially in aging persons. Recently the pleiotropic action of vit. D, also the influence on immune system, was shown and discussed. On the basis of randomly selected 723 women and men (382 men) over 65 yrs old from PolSenior Study we developed the frequency of SH in Polish aging population, and we compared the m...

Abstract Objectives Laboratory services are an important part of the healthcare system. However many requested tests may be considered inappropriate or unnecessary. We evaluated laboratory use in a period 3 years terms test repeats. Methods analyzed repeat rate (IRR) hemoglobin A1c (HbA1c), 25-OH vitamin D [25(OH)D], thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), thyroxine (FT4...

OBJECTIVE To find the prevalence of thyroid autoimmunity in PCOS women of reproductive age group. METHODS Study design: Observational study was done at ESIMC and PGIMSR K.K. Nagar March 2013-Feb 2014. Ninety cases of women with PCOS based on Rotterdam's criteria and an equal number of age-matched controls (women without PCOS) were included in the study. Thyroid profile, antithyroid peroxidase...

OBJECTIVE The aim of the present study was to determine the prevalence of abnormal thyroid function and antithyroid antibodies during pregnancy in women with diabetes type 1 and gestational diabetes mellitus (GDM). METHODS The study group included 83 pregnant women who attended the Outpatient Department of the Endocrinology, Diabetes and Metabolic Disorders Clinic in the period from 05.2009 t...

OBJECTIVE To investigate thyroid autoimmunity in a very large nationwide cohort of children and adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS Data were analyzed from 17,749 patients with type 1 diabetes aged 0.1-20 years who were treated in 118 pediatric diabetes centers in Germany and Austria. Antibodies to thyroglobulin (anti-TG) and thyroperoxidase (anti-TPO) were measured ...

PURPOSE High prevalence of thyroid disorders is more common in type 1 diabetes compared to type 2 diabetes, due to associated autoimmunity. Hypothyroidism is the most common disorder. The objective was to assess the prevalence of thyroid dysfunction among type 2 diabetic Egyptian females and to find the correlation between metabolic syndrome components and autoimmune thyroid dysfunction. MATE...

introduction: imatinib, a tyrosine kinase inhibitor which resulted in much improvement in the treatment of chronic myelogenous leukemia (cml), may adversely affect thyroid gland function. to date, assessment of thyroid function during imatinib therapy has limited to retrospective studies. the aim of this study was to evaluate the effects of imatinib on thyroid function in a prospective manner. ...

autoimmune thyroid diseases (atd) are multifactorial conditions that result from genetic predisposition in combination with environmental risk factors. helicobacter pylori infection as an environmental risk factor has been proposed to imitate the antigenic components of the thyroid cell membrane and may play a leading role in the onset of the autoimmune diseases, such as hashimoto thyroiditis. ...

OBJECTIVE To prospectively evaluate the heterogeneous appearance of the thyroid gland, reflecting inflammation and destruction in euthyroid Hashimoto's thyroiditis (HT), we investigated the clinical utilities of the heterogeneity index (HI) [the coefficient of variance (CV) of the ultrasonographic (US) intensities], focusing on anti-thyroid peroxidase antibodies (TPO-Ab), which represent not on...