Background and objectives: Diabetes is a metabolic disease with hyperglycemia, decrease in insulin secretion or de-sensitization of peripheral cells to insulin.Onosmadichroanthum is a species of Boraginaceae and is used in traditional medicine for its anti-oxidant, anti-inflammatory and antibiotic properties, however data on its anti-diabetic effects ...

We investigated whether low-dose radiation (LDR) can prevent late-stage diabetic cardiomyopathy and whether this protection is because of the induction of anti-apoptotic and anti-oxidant pathways. Streptozotocin-induced diabetic C57BL/6J mice were treated with/without whole-body LDR (12.5, 25, or 50 mGy) every 2 days. Twelve weeks after onset of diabetes, cardiomyopathy was diagnosed characteri...

Numerous studies have demonstrated that aged black garlic (ABG) has strong anti-oxidant activity. Little is known however regarding the anti-inflammatory activity of ABG. This study was performed to identify and compare the anti-oxidant and anti-inflammatory effects of ABG extract (ABGE) with those of fresh raw garlic (FRG) extract (FRGE). In addition, we investigated which components are respo...

Cells generate unpaired electrons, typically via oxygen- or nitrogen-based by-products during normal cellular respiration and under stressed situations. These pro-oxidant molecules are highly unstable and may oxidize surrounding cellular macromolecules. Under normal conditions, the reactive oxygen or nitrogen species can be beneficial to cell survival and function by destroying and degrading pa...

Objective(s): The present study sought to evaluate the beneficial effects of histidine (His) on oxidative stress, tumor necrosis factor alpha (TNF-α), renal histological alterations and anti-oxidant enzymes gene expressions in type 2 diabetic rats.Materials and Methods: Streptozotocin/nicotinamide (STZ/NA) induced diabetic rats were used...

Phytochemicals show many desirable functions such as anti-oxidant, anti-microbial, anti-inflammatory, anti-carcinogenic, anti-ageing, activities and so on.These biological can only be seen when the compounds are delivered at sufficient concentrations. However, bioavailability of phytonutrients suffers from their limited absorption, transformation, rapid clearance circulation. In this review, we...

Introduction: Salvia hispanica L. is an annual herbaceous plant commonly known as "Chia", native of southern Mexico and northern Guatemala. The aim this study isolation, identification secondary metabolites evaluation biological activities ethyl acetate fraction aerial parts. Methods: Air dried powdered parts was extracted by maceration fractionated using light petroleum, dichloromethane solven...

to investigate the ulcer protective and antisecretory properties of the methanolic extract of butea monosperma (bm) bark with relation to antioxidant studies. the study was done on male albino rats.   gastric ulcers were induced by aspirin, alcohol and pylorous ligation. lansoprazole was used as the standard drug for comparison. the free radical scavenging potential of the bark of bm extract wa...