Hyaline fibromatosis syndrome (HFS) is rare autosomal recessive disease characterized by the deposition of amorphous hyaline material in skin and visceral organs. It represents a disease spectrum with infantile systemic hyalinosis (ISH) being the severe form and juvenile hyaline fibromatosis (JHF) being the mild form. Dermatologic manifestations include thickened skin, perianal nodules, and fac...

We conducted a prospective, randomized, unblinded, controlled trial of exogenous bovine surfactant (surfactant TA) in premature infants requiring ventilator support for the treatment of severe hyaline membrane disease. Forty-one low birth weight infants with severe hyaline membrane disease were randomly assigned to saline or surfactant therapy and treated within eight hours of birth. Significan...

Myxopapillary ependymomas (MPEs) are uncommon and account for ∼15% of all ependymomas. The current study presents a case of rare spinal MPE with abnormal hyaline degeneration. The patient was a 72-year-old male with a 10-month history of lower back pain. Magnetic resonance imaging revealed a mass involving the L4 and L5 vertebrae with local bone destruction. The tumor was completely resected. H...

An increase in the degree of fatty change of the liver was found by Benitez (1952) in babies who had aspirated vernix caseosa or who had pulmonary hyaline membranes, but little else has been recorded about hepatic lesions in such cases. The observation of small thrombi in the sinusoids of the livers of babies with hyaline membranes was thus of interest; the investigation reported in this paper ...

The histological features of 168 lesions of Kaposi's sarcoma from 159 patients in Malawi, where the disease is commoner than elsewhere, were characteristic. All showed well-developed areas of tumour and could be grouped fairly readily into those with a mixed pattern, a predominantly spindle cell pattern, and an anaplastic group, though intermediate patterns were seen. Hyaline bodies were presen...

The treatment of focal full thickness articular defects in the knee has continued to present a challenge, with no traditional treatment method providing consistent acceptable long-term clinical results. Patients with significant chondral defects frequently have persistent joint line pain, swelling, and catching in the knee. In contrast to marrow stimulation treatment techniques, such as abrasio...

castleman’s disease (angiofollicular lymphoid hyperplasia) includes a heterogeneous group of lymphoproliferative disorders. the cause of this disease remains uncertain. there are two types of localized castleman’s disease: the more common hyaline vascular and the plasma cell types. mixed variant is an uncommon localized lesion in general population. the lesions can occur in any part of the body...

Alflutop is the standardized sterile extract of marine fish, similar in composition to matrix hyaline cartilage, manufactured by Biotehnos S.A. (Romania). The question effectiveness aflutop remains relevant.

The presence of hyaline eosinophilic inclusions in protoplasmic astrocytes of cerebral cortex is a rare finding that is mostly associated with history of intractable epilepsy and cases of Aicardi syndrome. Here, we describe a 17-year-old male who presented with a longstanding history of intractable epilepsy. Microscopic examination of the excisional biopsy of the epileptic focus showed hyaline ...