The tissue antigen HLA-B27 is found in 50% of Dutch acute anterior uveitis (AAU) patients. The prevalence of HLA-B27 in the normal population is only 8%. However, only approximately 1% of HLA-B27+ individuals will develop AAU. Therefore, it is possible that the disease is associated with a particular B27 subtype. We typed lymphocytes of 36 B27+ AAU patients, of which 20 also had ankylosing spon...

Uveitis denotes inflammation of the uveal tract of the eye and is generally categorised as either anterior (involving the iris/ciliary body) or posterior (involving the choroid as well as adjacent structures including pigment epithelium and retina). Although uveitis is a known cause of blindness, until recently there were few data reflecting the prevalence and incidence of uveitis among the bli...

PURPOSE To report the results of a retrospective analysis among endogenous uveitis patients in the north-eastern area of Italy. METHODS The authors reviewed a series of 655 new cases treated between October 1986 and December 1993. The incidence of endogenous uveitis was calculated based on a 100,000 patient population. RESULTS The average incidence was 11.40/100,000. The majority of patient...

BACKGROUND The purpose of this study was to assess the efficacy of oral valganciclovir in the treatment of anterior segment inflammation caused by cytomegalovirus (CMV) infection. METHODS Consecutive patients with anterior segment inflammation due to CMV causing anterior uveitis or corneal endotheliitis treated with oral valganciclovir were reviewed. Diagnosis of CMV infection was confirmed b...

PURPOSE This study aimed to analyze the clinical patterns and etiology of uveitis in Isfahan, Iran. METHODS In this descriptive research, the records of 2016 patients with uveitis referred to a tertiary eye care centers were examined. Age, sex, clinical and anatomical features, and etiology of disease were recorded and analyzed. RESULTS The mean age of onset of uveitis was 33.76 years and t...

Three hundred and fifteen patients with anterior uveitis associated with juvenile chronic arthritis (JCA) were studied in order to identify the various risk factors for uveitis. Girls were more susceptible to uveitis than boys by a ratio of 3:1. In 94% of cases the uveitis was diagnosed after the development of arthritis. The risk of uveitis was small after seven or more years had elapsed from ...

purpose: to compare the results of three-piece and one- piece hydrophobic acrylic posterior chamber intraocular lens (iol) with poly methyl metacrylate (pmma) iol implanted during lensectomy, posterior capsulotomy and anterior vitrectomy for congenital or developmental cataract. methods: this is a historical cohort study conducted on patients with congenital or developmental cataract who underw...

BACKGROUND Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness. FINDINGS We report the case of a 15-year-old girl who presented with acute granulomatous iridocyclitis and was diagnosed with TINU ...

Acute anterior uveitis (AAU) is the most common form of intraocular inflammation seen by eye care professionals that affects relatively younger patients, with significant distress and potentially long-lasting sight-threatening complications. The diagnosis of AAU is relatively simple for clinicians because of multiple presenting signs and symptoms; however, the etiology is often much more diffic...

BACKGROUND The study aims to report the association between successful uveitis control following anti-tuberculous therapy (ATT) for uveitis associated with a positive tuberculosis (TB) screening test in a low endemic setting. A retrospective chart review of cases between 2010 and 2017 at a tertiary uveitis referral center in the United States of America was conducted. Subjects with any form of ...