The enzymes which transcribe DNA synthesizing RNA (DNA-dependent RNA polymerases) have structural differences in eukaryotic and prokaryotic cells, as indicated by the fact, among others, that there are substances which inhibit their function selectively in prokaryotic cells (streptolydigin and the ansa antibiotics, such as rifamycins and streptovaricin) and in eukaryotic cells (-amanitin). Ansa...