Specific anatomic features are risk factors for primary angle closure glaucoma (PACG), a dominant type of glaucoma in Asia. Some tissue remodeling genes have been reported associated with PACG. A Genome-wide association study identified three new susceptibility loci for PACG. However, the exact mechanism of these genes in PACG pathogenesis is still unclear. This commentary summarized the correl...

PURPOSE To report a case of bilateral acute angle-closure glaucoma after oral administration of cabergoline for the treatment of galactorrhea. METHODS A diagnosis of secondary drug-induced angle-closure glaucoma was made in a patient with elevated intraocular pressure (IOP) and myopic refractive shift, which was confirmed by ultrasound biomicroscopy (UBM) of the ciliary body and anterior segm...

Phacoemulsification in angle closure can be challenging. Many factors, including large lens, small pupil and a narrow working space in the anterior chamber, contribute towards an increased level of difficulty. Angle closure eyes are also often associated with increased risk of complications such as malignant glaucoma and suprachoroidal hemorrhage. For the inexperienced or the unsuspecting, phac...

AIM To determine the prevalence of preglaucomatous angle-closure disease in central Myanmar. METHODS A population-based survey of inhabitants >or=40 years in the Meiktila District was carried out; 2481 subjects were identified, 2076 participated and 2060 underwent gonioscopy of at least one eye. Eyes with angles traditionally described as "occludable" were recorded as primary angle-closure su...

BACKGROUND To describe the surgical technique and refractive outcomes following clear lens extraction (CLE) in the Effectiveness, in Angle-closure Glaucoma, of Lens Extraction trial. METHODS Review of prospectively collected data from a multicentre, randomised controlled trial comparing CLE and laser peripheral iridotomy. Eligible participants were ≥50 years old and newly diagnosed with (1) p...

PURPOSE To determine the prevalence of appositional angle closure (AAC) after laser peripheral iridotomy (LPI) in the eyes of Chinese patients with primary angle closure (PAC) and primary angle closure glaucoma (PACG) and to evaluate its pathogenesis by investigating anatomic characteristics. METHODS This was a cross-sectional observational study. PAC and PACG subjects were consecutively enro...