The amino acid sequences of the V (variable) regions of the H (heavy) and L (light) chains derived from rabbit antibody K-25, specific for type III pneumococci, were determined; this is the second homogeneous rabbit antibody besides antibody BS-5 whose complete sequence of the V domain has been established (Jaton, 1974d). The V regions of L chains BS-5 and K-25 (both of allotype b4) differ from...

T'b is comilitmication emphasizes the nieed for conltin1uouts conitrol of pH when macerating acidic plant tissues for the l)url)ose of isolating tightly coupled mitochondria. A useful device for such control is described. Mitochonidria capable of oxidative but not pl)osphorylative activity have been isolated fromli apple fruits wlhenl either alkaline homogeniates (5) or l)oIyvinylpyrrolidone (P...

Photosynthetic phosphorylation has been studied in (letail in a wxide variety of higher plants andl photosynthetic bacteria, but to date only a few investigations have been made in the algae. Although a high rate of photosynthetic phosphorylation has been reported for cell-free preparations of the blue-green alga A iabaena z,ariabilis (11), only fragmentary data are available describing this pr...

Nitric oxide (NO) synthesis inhibition with N G-nitro-l-arginine methyl ester (l-NAME) (10 μg ⋅ kg-1 ⋅ min-1iv), cyclooxygenase inhibition with meclofenamate (Meclo; 5 mg/kg iv bolus), and combination of drugs (l-NAME+Meclo) were used to investigate the roles of NO and prostaglandins (PG) in the hemodynamic and natriuretic responses to isotonic saline volume expansion (VE; 5% body wt over 60 mi...

The purpose of this study was to determine whether methotrexate modulates bradykinin-induced increase in macromolecular efflux from the in situ oral mucosa and whether this response is mediated by thel-arginine/nitric oxide biosynthetic pathway. Using intravital microscopy, we found that suffusion of methotrexate alone onto the hamster cheek pouch had no significant effects on leaky site format...

The effects of prefumigation light regimes on plants indicate that light modifies the response of plants to ozone. Taylor et al. (11) reportecl that ozone injury to Pinto bean was reduced when plants were grown at the higher level of 2 light intensities. Menser et al. (7) foundl that ozone danmage to tobacco plants was diminished by an extendedl 22-hour photoperiod immediately before funmigatio...

During the immunodiagnosis of 517 cases of acute myelogenous leukemia (AML) entered into the Medical Research Council (MRC) AMLIO trials, we have observed the CD34 precursor cell antigen more frequently in AML of M2 morphology, especially in the 84% of cases with the t(8;21) chromosomal translocation, than in any other French-AmericanBritish classification group. CD34 expression was then quanti...

You know the feeling—while reading an article on a topic related to your own research, you gradually become aware of a strong similarity between the ideas expressed and those you published some time ago. A quick glance at the references cited shows you that your article isn’t mentioned. If the author is known to you, and you are confident that he or she knows about your work, then you have to d...

The application of high concentrations of 2,4(lichlorophenoxyacetic acid (2,4-D) to plants results in increased nucleic acid content (4, 11, 17, 22). The RNA synthesized is largely ribosomal (4,13). Since IAA will also induce increases in nucleic acids (6, 19) the auxin properties of 2,4-D are presunmably involved. If basal stem tissues of soybean (13) or corn (22) seedlings are incubated with ...

Though light induced reproduction, both sexual an(l asexual, is common to many fungi (15), the mlechanisnm ;of this phenomenon is not un(lerstood. Suggestions have been made on the possible nature of a photoreceptor pigment involved (5) but there has been little experimental evidence to support or refute these views. Recent studies with .4scochyta pisi, Lib. (9), Pleospora herbarunm (Pers.) Rab...