نتایج جستجو برای: analyzed using pca
تعداد نتایج: 3659678 فیلتر نتایج به سال:
Background: Triptolide is a medicinal herb-derived diterpene triepoxide with potent anti-tumor activity, mainly ,correlated with its ability to inhibit and inactivate subunits of RNA polymerase II, thereby suppressing global gene transcription. Epigenetic imbalance including histone methylation are well known to play important roles in prostate cancer (PCa) onset and progression. The goal of th...
Transforming growth factor β1 (TGFβ1) regulates a variety of cellular functions, including cell growth, apoptosis and differentiation. The aim of the current study was to investigate the alterations of phenotypic events in the long-term exposure of prostate cancer (PCa) cells to TGFβ1 and its effect on macrophage-differentiated cells. The PCa cell line, PC-3, and the subclone, M1, were exposed ...
BACKGROUND Prostate cancer (PCa) detection using serum-based prostate specific antigen (PSA) is limited by frequent false-positive and -negative results. Genetic aberrations such as allelic imbalance (AI) and epigenetic changes such as promoter hypermethylation have been detected in circulating DNA of cancer patients. We hypothesized that circulating multimarker DNA assays detecting both geneti...
abstract pragmatics is the study of communicative action in its sociocultural context. communicative action includes not only using speech acts (such as apologizing, complaining, complimenting, and requesting), but also engaging in different types of discourse and participating in speech events of varying length and complexity. the present study aimed to investigate the assessment of pragm...
PURPOSE The aim of this study was to assess the fractal dimension (Df) of disks with 3 different surface topographies. MATERIALS AND METHODS Thirty disk-shaped samples (10 × 2 mm) with 3 different surface topographies (Dental Tech, Misinto, Italy) were analyzed by scanning electron microscopy: group A, machined surface; group B, titanium plasma-spray surface; group C, acid-etched and sandblas...
the study area covers the northern part of the baft geological map (scale of 1:100 000 ). several porphyry and vein-type mineralization are reported from this area. a topic that is discussed in the mineral exploration community is the use of remote sensing and airborne geophysics for porphyry type mineralization. which one is more reliable and efficient in hydrothermal alteration mapping? airbo...
INTRODUCTION To date, only few studies focusing on the issue of host general and immune activity have been performed in localized prostate cancer (PCa). The aim of this study was to elucidate potent non tumor-related biomarkers that express aggressiveness of PCa treated by radical prostatectomy (RP). MATERIALS AND METHODS Data from 179 patients who underwent RP were analyzed. The correlations...
PURPOSE Opioid-based intravenous patient-controlled analgesia (IV PCA) is popular method of postoperative pain control, but many patients suffer from IV PCA-related postoperative nausea and vomiting (PONV). In this retrospective observational study, we have determined independent predictors of IV PCA-related PONV and predictive values of the Apfel's simplified risk score in pursuance of identif...
Intrusion detection systems IDS are increasingly utilizing machine learning methods. IDSs important tools for ensuring the security of network data and resources. The Internet Things (IoT) is an expanding intelligent machines sensors. However, they vulnerable to attackers because ubiquitous extensive IoT networks. Datasets from intrusion (IDS) have been analyzed deep methods such as Bidirection...
Metastasis is the primary cause of death in prostate cancer (PCa) patients. Small nucleolar RNAs (snoRNAs) have long been considered "housekeeping" genes with no relevance for cancer biology. Emerging evidence has challenged this assumption, suggesting that snoRNA expression is frequently modulated during cancer progression. Despite this, no study has systematically addressed the prognostic and...
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