Molecular mechanisms underlying health and disease function at least in part based on the flexibility and fine-tuning afforded by protein isoforms and post-translational modifications. The ability to effectively and consistently resolve these protein species or proteoforms, as well as assess quantitative changes is therefore central to proteomic analyses. Here we discuss the pros and cons of cu...

Gas chromatography-mass spectrometry (GC-MS) is a widely used analytical technique in metabolomics. GC provides the highest resolution of any standard chromatographic separation method, and with modern instrumentation, retention times are very consistent between analyses. Electron impact ionization and fragmentation is generally reproducible between instruments and extensive libraries of spectr...

Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) has emerged as an important analytical tool supporting product development and problem solving for customers in the automotive, coatings, electronics, glass, life sciences, and pharmaceutical markets. Typical analyses include the chemical characterization of surfaces, lateral imaging, depth profiling, identification of trace impurities, ...

The paper discusses the development of rhetorical analyses of political addresses from classical antiquity to modern political communication. A specific genre, the ‘epideictic address’, is described in detail. It concerns addresses by representative persons. Most epideictic addresses turn out to be ‘hybrid’ texts because they combine an orientation towards (rhetorical-political) persuasion with...

Free and total sulfite were analyzed in acidified vegetable products, instant mashed potatoes, and dried apples. Sulfite was separated by HPLC and quantified with a UV-vis detector. Resolution from components of food samples was achieved by varying the acid concentration of the eluant solution and by appropriate choice of the analytical wavelength. The minimum detectable levels for sulfite were...

An analytical computation of the magnetic field distribution in a wholly superconducting synchronous reluctance motor is proposed. The stator of the studied motor consists of three-phase HTS armature windings fed by AC currents. The rotor is made with HTS bulks which present the specificity to have a diamagnetic behavior under zerofield cooling. The electromagnetic torque is obtained by the int...

Developing internally valid, and perhaps generalizable, farmworker exposure studies is a complex process that involves many statistical and laboratory considerations. Statistics are an integral component of each study beginning with the design stage and continuing to the final data analysis and interpretation. Similarly, data quality plays a significant role in the overall value of the study. D...

Amplicon (targeted) sequencing by massively parallel sequencing (PCR-MPS) is a potential method for use in forensic DNA analyses. In this application, PCR-MPS may supplement or replace other instrumental analysis methods such as capillary electrophoresis and Sanger sequencing for STR and mitochondrial DNA typing, respectively. PCR-MPS also may enable the expansion of forensic DNA analysis metho...

This paper deals with the analytical computation of the magnetic field distribution in a wholly superconducting reluctance motor. The rotor is made with high temperature superconductor bulks which nearly present a diamagnetic behavior under zero-field cooling. The stator consists of superconducting armature windings fed by AC currents of high amplitude. The superconducting stator winding can ge...

Analytical competency in classroom situations can be seen as a crucial aspect of teachers’ professional competency. While case-based learning is considered to have great potential for the promotion of analytical skills of teachers, there have been few attempts to investigate the effects of corresponding instructional support. The empirical study presented here investigates the effects of instru...