Background: SLE clinical manifestations and course are highly variable, ranging from indolent to fulminant by the production of antibodies to cell nucleus components and also towards cytoplasmic antigens. Autoantibodies helps to diagnose SLE appropriately. The present study is undertaken to know the varied clinical features of SLE prevalence and also to know the ANA profile in relation to SLE. ...

Certain drugs are a frequent source of antinuclear antibody (ANA) induction, and ANA is invariably present in the few patients who progress to the drug induced lupus syndrome. This report concerns the fine specificity of the ANA response to hydralazine, penicillamine, and sulphasalazine therapy. Using highly purified individual histones in fluorimetric assays, antihistone antibodies are always ...

The ANA test is an excellent screening test for patients with SLE and a few other connective tissue diseases. The LE cell preparation is an assay that is subjective and costly. Because of the presence of a superior screening test (the ANA) and superior specific auto-antibody tests, the author recommends that the use of LE cell preparations be discontinued. ANA screening tests may be performed e...

We compared the susceptibility results for 200 clinical anaerobes with nine antibiotics obtained by using a new ATB ANA (bioMérieux) device against those obtained by the National Committee for Clinical Laboratory Standards (NCCLS) standard agar dilution method. For better evaluation of the device, we added some resistant Bacteroides fragilis group strains from our own collection: 3, 6, and 12 s...

The atmospheric conditions that lead to strong offshore surface winds in Southern California, commonly referred to as Santa Ana winds, are investigated using the North American Regional Reanalysis and a 12-year, 6-km resolution regional climate simulation of Southern California. We first construct an index to characterize Santa Ana events based on offshore wind strength. This index is then used...

In a comparative study of antinuclear antibodies (ANA) and immune complexes in the serum of 43 patients with systemic sclerosis (SS) ANA were detected by indirect immunofluorescence on Hep 2 cells and/or double immunodiffusion in 90% of patients, while immune complex assays were positive in 32% of patients. The immune complex assays were positive only in sera containing antibodies to Scl 70, n-...

Quantification of IgM molecular response by droplet digital PCR as a potential tool for the early diagnosis of sepsis Eduardo Tamayo, Raquel Almansa, Elena Carrasco, Ana Ávila-Alonso, Ana Rodríguez-Fernández, John Wain, María Heredia, Esther Gomez-Sanchez, Susana Soria, Lucia Rico, Verónica Iglesias, Ángel Martínez-Martínez, David Andaluz-Ojeda, Jose Ignacio Gómez Herreras, Jose Maria Eiros and...

Amanda Gonçalves ([email protected]) Ingrid P Ewald ([email protected]) Marina Sapienza ([email protected]) Manuela Pinheiro ([email protected]) Ana Peixoto ([email protected]) Amanda F Nobrega ([email protected]) Dirce M Carraro ([email protected]) Manuel R Teixeira ([email protected]) Patricia Ashton-Prolla ([email protected]...

Lia Beatriz de Azevedo Souza Karbage, Ana Paula Dias Rangel Montenegro, Luciana Felipe Férrer Aragão, Izabella Tamira Galdino Farias Vasconcelos, Virgínia Oliveira Fernandes, Annelise Barreto de Carvalho, Clarisse Mourão Melo Ponte, Catarina Brasil D'Alva, Carla Soraya Costa Maia, Synara Cavalcante Lopes, Marivaldo Loyola Aragão, Carla Antoniana Ferreira de Almeida Vieira, Ana Paula Germano Lop...

Ana Paula Silva1*, André Fragoso1, Cláudia Silva2, Nelson Tavares3, Nélio Santos2, Hercília Martins2, Kristina Gundlach4, Janine Büchel4, Ana Camacho3, Marília Faísca5, Ilídio Jesus Varela3 and Pedro Neves1 1Department of Nephrology, Hospital Faro, Faro, Portugal 2Pathology Clinic, Hospital Faro, Faro, Portugal 3Department of Cardiology, Hospital Faro, Faro, Portugal 4Fresenius Medical Care Deu...