The aim of this paper was to describe a clinical case of immediate dental desensitization using a self-etch adhesive system in an adolescent patient diagnosed with amelogenesis imperfecta (AI). AI was associated with severe tooth sensitivity, treated by the application of a universal adhesive system for desensitization of the teeth affected by AI. Reduction of tooth sensitivity was assessed usi...

Molar incisor hypomineralization (MIH) is a congenital disease which is increasing in prevalence. It affects permanent first molars and, often to a lesser degree, permanent incisors with variable severity. The etiology is unknown, but various risk factors have been put forward. Differential diagnosis is mandatory not to confound MIH with other diseases such as amelogenesis imperfecta or fluoros...

Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and -19 are pore forming TJ proteins allowing calcium and magnesium reabsorption in the thick ascending limb of Henle's loop (TAL). Loss-of-function mutations in the encoding genes, initially identified to cause Familial Hypomagnesemia with Hypercalciuria and Ne...