A doença de Alzheimer vem se tornando cada vez mais comum entre os idosos, uma neurológica degenerativa, progressiva e irreversível. O tratamento é realizado por meio medicamentos com o objetivo minimizar distúrbios da e, dentre tratamentos farmacológicos existentes, destacam-se aqueles base na Cannabis sativa. estudo, teve como Analisar literatura científica uso terapêutico sativa no Alzheimer...

Alzheimer disease is the most common form of dementia and has a significant impact on mortality in the senior population. A vast amount of information has emerged over the past decade especially in regards to the underlying genetics and the significance of intrinsic and extrinsic risk factors. The importance of identifying risk factors may provide critical information to prioritize those patien...

Gamification can provide new perspectives to help training people with Alzheimer and their caregivers. In this paper is shown the technical and social feasibility of launching on the market a serious game for training of Alzheimer`s caregivers. A use case in the north of Spain has been selected. Before that, a state of art of serious games in the field of dementia has been done. The study showe...

While there is ample experimental evidence supporting the role of estrogen in the pathogenesis of Alzheimer disease, recent inconclusive data regarding hormone replacement therapy (HRT), specifically, the unexpected results of the Women's Health Initiative (WHI) Memory Study has raised serious questions regarding the protective effects of estrogen. Because of this and other inconsistencies in t...

Many lines of evidence suggest that oxidative stress is important in the pathogenesis of Alzheimer disease. In particular, beta-amyloid, which is found abundantly in the brains of Alzheimer disease patients, is toxic in neuronal cell cultures through a mechanism involving free radicals. Vitamin E prevents the oxidative damage induced by beta-amyloid in cell culture and delays memory deficits in...

BACKGROUND Neurofibrillary tangles and beta-amyloid plaques have been observed in the amygdala in Alzheimer disease. A disproportionate abundance of this abnormality in the amygdala may cause behavioral symptoms similar to Klüver-Bucy syndrome. OBJECTIVES To describe an atypical behavioral presentation of Alzheimer disease and to review the literature on the subject. DESIGN Case study. SE...

On Nov 4, 1906, Alois Alzheimer gave a remarkable lecture, in which he described for the first time a form of dementia that subsequently, at the suggestion of Emil Kraepelin, became known as Alzheimer’s disease. In his lecture, at the 37th Conference of South-West German Psychiatrists in Tübingen, Alzheimer described a patient called Auguste D, a 51-year-old woman from Frankfurt who had shown p...

background: metal ions effect on homeostasis of alzheimer’s disease (ad) patients. the aim of this study was to assess the metal ions (iron, zinc and copper) and cbc in patients with ad in comparison with normal range. methods: the samples of study were 17 patients with ad in tehran’s aging centers in 2015, selected as an access sample. blood samples were analyzed in a pathobiology laboratory. ...

background: sporadic alzheimer’s disease (sad) is caused by genetic risk factors, aging and oxidative stresses. the herbal extract of rosa canina (r. canina), tanacetum vulgare (t. vulgare) and urtica dioica (u. dioica) has a beneficial role in aging, as an anti-inflammatory and anti-oxidative agent. in this study, the neuroprotective effects of this herbal extract in the rat model of sad was i...