BACKGROUND The failure of intestinal mucosal barrier may induce multiple organ dysfunction and systemic inflammatory response syndrome, but little work has been done on whether hypobaric hypoxia related to the failure of intestinal mucosal barrier. AIMS To study the expression of hypoxia-inducible factor 1α (HIF-1α), inducible nitric oxide synthase (iNOS) and morphological changes of intestin...

Recent studies have demonstrated that brief daily IAE (intermittent altitude exposure) was equally as effective as continuous altitude residence in inducing physiological adaptations consistent with altitude acclimatization. Although the positive benefits of IAE have been clearly defined, the potential negative consequences of IAE on health, specifically the immune system, remain undefined. The...

Acclimatisation to environmental hypoxia initiates a series of metabolic and musculocardio-respiratory adaptations that influence oxygen transport and utilisation, or better still, being born and raised at altitude, is necessary to achieve optimal physical performance at altitude, scientific evidence to support the potentiating effects after return to sea level is at present equivocal. Despite ...

rashe grape cultivar grows in kurdistan province in rain fed conditions. microclimate conditions have a great effect on grape berry quality. information about changes in grape berry composition in the relation to climate changes is limited. in order to measure the effects of slope and altitude on some grape berry chemical composition, a study was conducted on grape cv. ‘rasheh’ in university of...

This paper is devoted to the study of the eigenpairs of the Dirichlet Laplacian on a family of triangles where two vertices are fixed and the altitude associated with the third vertex goes to zero. We investigate the dependence of the eigenvalues on this altitude. For the first eigenvalues and eigenfunctions, we obtain an asymptotic expansion at any order at the scale cube root of this altitude...

The purpose of this paper is to perform the feasibility and performance evaluation of the High-altitude launch technique using high altitude atmospheric Properties to near earth orbits. The current propulsion transportation system from Earth to space has been deemed by many to be expensive, unreliable, and an unnecessarily dangerous means of travel to space. It is suggested in this paper to ana...

Acute mountain sickness (AMS) and large decrements in endurance exercise performance occur when unacclimatized individuals rapidly ascend to high altitudes. Six altitude and hypoxia preacclimatization strategies were evaluated to determine their effectiveness for minimizing AMS and improving performance during altitude exposures. Strategies using hypobaric chambers or true altitude were much mo...

hail phenomenon is one of the hazardous weather phenomena that can make the highest amount of damage to farms, gardens, cars, rooftops, etc. in a very short time (a few minutes), depending on the diameter of the particles. one of the best ways to study this devastating climatic phenomenon is the use of atmospheric instability indices. the indices which are calculated with the help of radiosonde...