The Au(I)-catalyzed cyclization of hydroxyallylic ethers to form tetrahydropyrans is reported. Employing (acetonitrile)[(o-biphenyl)di-tert-butylphosphine]gold(I) hexafluoroantimonate, the cyclization reactions were complete within minutes to hours, depending on the substrate. The reaction progress was monitored by GC, and comparisons between substrates demonstrate that reactions of allylic alc...

The chemoenzymatic synthesis of a Lewis basic phosphine-phosphine oxide organocatalyst from a cis-dihydrodiol metabolite of bromobenzene proceeds via a palladium-catalysed carbon-phosphorus bond coupling and a novel room temperature Arbuzov [2,3]-sigmatropic rearrangement of an allylic diphenylphosphinite. Allylation of aromatic aldehydes were catalysed by the Lewis basic organocatalyst giving ...

Generations 1 to 3 of dendrimers ended by water-soluble phosphines are synthesized and their ruthenium complexes are used as catalysts in aqueous media; a slightly positive dendritic effect on the regioselectivity is observed for hydration of alkynes and a large positive dendritic effect is observed in the biphasic (water/heptane) catalysed isomerisation of allylic alcohols to ketones where the...

A. Primary Alcohols as Nucleophiles 2931 B. Carboxylates as Nucleophiles 2931 C. Alkylations with Phenols 2932 IV. Nitrogen Nucleophiles in AAA Total Synthesis 2935 A. Alkylamines as Nucleophiles 2935 B. Azides as a Nucleophile 2936 C. Sulfonamide Nucleophiles 2937 D. Imide Nucleophiles 2938 E. Heterocyclic Amine Nucleophiles 2940 V. Sulfur Nucleophiles 2941 VI. Summary and Conclusions 2941 VII...

This thesis describes methods to obtain value–added compounds from TMPturpentine obtained from the spruce, Picea abies. The methodology focuses on biotransformations using two approaches: an oxygenation approach (i.e. oxygenation of terpene hydrocarbons by cell cultures) and an esterification approach (i.e. lipase-catalysed transesterification of vinyl acetate with terpene alcohols, and a furth...