Background The double-blind placebo-controlled food challenge (DBPCFC) is considered to be the gold standard for diagnosing food allergy in children. During the DBPCFC, both objective and subjective symptoms are observed. Although subjective symptoms are thought to be less specific than objective symptoms, it is not known whether objective symptoms have a stronger association with a true positi...

Reducing inappropriate antibiotic prescribing in primary care is a key element of antimicrobial stewardship. This study carried out GP surgeries Cornwall examined whether clarithromycin was being prescribed accordance with NICE guidance, and allergy status symptoms were correctly recorded the case patients who had penicillin noted.

Recently, the prevalence of allergies in Japan has been increasing. Certain types of fruit juice and lactic acid bacteria are known to alleviate allergic symptoms. Therefore, we examined whether citrus juice fermented by a specific lactic acid bacteria can improve the symptoms of Japanese cedar pollinosis (JCPsis). Lactobacillus plantarum YIT 0132 (LP0132) was selected based on its high prolife...

BACKGROUND Lupin, a legume with good nutritional value, is used in food production today, most often in bakery products. Lupin sensitization is often seen among patients with reactions to legumes, but the number of reports describing lupin anaphylaxis is also increasing. OBJECTIVE To investigate the occurrence of lupin sensitization, cross-reactivity, and lupin allergy among patients with sus...

Results 278 patients, 232 adults (83.5%) and 46 children (16.5%) have been analyzed. The mean age in adults was 34 years (IQR: 26-44) and in children 5 years (IQR: 3-7). 57.2% were women and 42.8% men. 70% had a personal history of atopic disease. Milk and egg, 28.3% each, were the more frequently implicated foods in children. In adults; nuts (39.4%), rosaceae fruits (29.9%) and shellfish (11.6...

The term pollen-food allergy syndrome (PFAS) defines a series of clinical symptoms appearing shortly after the ingestion of plant-derived foods in subjects with pollen allergy. The patients with PFAS are primarily allergic to pollen and subsequently react to food allergens as a consequence of the homology between pollen and plantfood proteins. The two highly conserved proteins responsible for t...

Fish allergy constitutes a severe problem worldwide. Its prevalence has been calculated as high 7% in paediatric populations, and many cases, it persists into adulthood with life-threatening signs symptoms. The following review focuses on the epidemiology of Immunoglobulin E (IgE)-mediated fish allergy, its pathogenesis, clinical manifestations, thorough approach to diagnosis management populat...

BACKGROUND The principle reason for referral to specialist allergy clinics is to establish diagnoses and provide treatment plans to help patients manage their allergy. If patients do not accept, understand, or remember diagnoses or treatment, clinic visits may have been a waste of time. Few specialist allergy clinics follow up patients after diagnosis. DESIGN AND METHODS This was a postal sur...

AIMS/BACKGROUND Nuclear transit studies (NTS) allow us to follow transit through the stomach and the small and large intestines. We identified children with chronic constipation with rapid proximal colonic transit and characterized their clinical features. METHODS We reviewed NTS from 1998 to 2009 to identify patients with chronic constipation and rapid proximal colonic transit, defined as gr...