asthma is a complex and multifactorial disorder. several studies have reported association between different hla- dqb1 and hla- drb1 alleles and allergic asthma. the aim of the present study was to investigate the association of hla-class ii alleles and haplotypes, with total serum ige and the results of the skin prick test in iranian children with allergic asthma. a total of 112 patients with ...

Objectives: As the prevalence of allergic diseases increases proportionately in Turkey, they retain their importance as diseases of childhood. The aim of this study was to determine the prevalence of asthma, allergic rhinitis and eczema in middle school students, and the related environmental factors. Methods: The sample of this cross-sectional study consisted of 1083 students in the 13-15 age ...

Background: Aloin, as a bioactive compound, has variety of pharmacological functions, but its effects on combined allergic rhinitis and asthma syndrome (CARAS) have not been studied. To clarify the protective effect mechanism aloin in treatment CARAS by network pharmacology, molecular dynamics simulation experiment. Methods: The targets aloin, were obtained from various databases. protein inter...

The aim . To determine the level of cathepsin S and to identify its possible relationships with clinical, functional laboratory indicators in patients severe bronchial asthma. Methods 114 asthma were examined. 96 women (84.2%) 18 (15.8%) men divided into 2 groups: allergic non-allergic external respiration function was assessed whole-body plethysmography (“Erich Jaeger”, Germany). plasma concen...

Bronchial asthma is recognized as a highly prevalent health problem in the developed and developing world with significant social and economic consequences. Increased asthma severity is not only associated with enhanced recurrent hospitalization and mortality but also with higher social costs. The pathogenetic background of allergic-atopic bronchial asthma is characterized by airway inflammatio...

Background The concept of Atopic march was developed to study the progress of Atopic Dermatitis to Allergic Rhinitis to Asthma. Epidemiologic studies have constantly demonstrated strong associations between Rhinitis and Asthma. Bronchial hyper-reactivity is an important component in the definition of Asthma. Many patients with Allergic Rhinitis have lower Airway hyperreactivity or bronchial hyp...

BACKGROUND There is considerable concern about the rising trend in the prevalence of asthma and allergic diseases. The ability to monitor this trend would be enhanced by the use of a biological marker for these diseases. OBJECTIVE This study investigated whether serum interleukin (IL) 12 and IL-18 levels were associated with allergic symptoms such as those of asthma, allergic rhinitis, and at...

BACKGROUND Sleep disordered breathing (SDB) and sleep disturbances have been reported to be associated with allergic rhinitis and asthma. However, population-based studies of this issue in the elderly are rare. OBJECTIVE To investigate the impact of self-reported rhinitis and asthma on sleep apnea and sleep quality using polysomnography in an elderly Korean population. METHODS A total of 34...

Asthma is a common chronic disease characterized by intermittent chest symptoms, variable airways obstruction, and bronchial hyperresponsiveness. Research performed over the past one to two decades has sought to better understand the heterogeneous clinical nature of asthma. Whereas older attempts at phenotyping asthma emphasized the duality of allergic vs. non-allergic asthma, more recent non-b...

Korean allergology has made great progress in keeping pace with global scientific advances in spite of a short history. Outstanding academic and scientific researches have been performed in a variety of allergy fields in Korea. Epidemiologic studies revealed increasing prevalence of asthma and allergic diseases and considerable morbidity and mortality in Korea. Novel inhalant allergens such as ...