The emerging viral diseases Haemorrhagic Fever with Renal Syndrome (HFRS) and Hanta virus Cardiopulmonary Syndrome (HCPS) are a cause of global concern as they are increasingly reported from newer regions of the world. Dengue also called classic dengue or break bone fever is a Flaviviral infection found in large areas of tropical & subtropical region. Clinically, the febrile illness produced by...

BACKGROUND The Rift Valley fever virus (RVFV) is a vector-borne virus that causes disease in ruminants, but it can also infect humans. In humans, the infection can be asymptomatic but can also lead to illness, ranging from a mild disease with fever, headache and muscle pain to a severe disease with encephalitis and haemorrhagic fever. In rare cases, death can occur. In infected animals, influen...

The incidence of dengue has grown dramatically around the world in recent decades. Over 2.5 billion people – over 40% of the world’s population – are now at risk from dengue. WHO currently estimates there may be 50-100 million dengue infections worldwide every year. Dengue Haemorrhagic Fever (DHF) affects most Asian and Latin American countries and has become a leading cause of hospitalization ...

Ebola haemorrhagic fever causes deadly disease in humans and non-human primates resulting from infection with the Ebola virus (EBOV) genus of the family Filoviridae. However, the mechanisms of EBOV lifecycle in host cells, including viral entry, membrane fusion, RNP formation, GP-tetherin interaction, and VP40-inner leaflet association remain poorly understood. This review describes the biologi...

To the editor: In their recent article, Macé et al. pointed appropriately to the many disturbing clinical similarities between haemorrhagic fever with renal syndrome (HFRS) due to Seoul virus (SEOV) infection – an emerging zoonosis – and two pregnancy-related pathologies affecting mainly the liver, acute fatty liver of pregnancy (AFLP) syndrome and haemolysis, elevated liver enzymes and low pla...

Viral haemorrhagic fevers (VHFs) are currently at the forefront of the world's attention due to the recent Zaire ebola virus epidemic in West Africa. This epidemic has highlighted the frailty of the world's public health response mechanisms and demonstrated the potential risks to nations around the world of imported cases of epidemic diseases. While imported cases in children are less likely, t...

In order to map global disease risk, a geographic database of human Crimean-Congo haemorrhagic fever virus (CCHFV) occurrence was produced by surveying peer-reviewed literature and case reports, as well as informal online sources. Here we present this database, comprising occurrence data linked to geographic point or polygon locations dating from 1953 to 2013. We fully describe all data collect...