نتایج جستجو برای: ali as

تعداد نتایج: 5648128  

Journal: :Journal of allergy & therapy 2011
Patrick A Singleton Frances E Lennon

Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), have high mortality rates with few treatment options. An important regulatory factor in the pathology observed in ALI/ARDS is a disruption of the pulmonary endothelial barrier which, in combination with epithelial barrier disruption, causes leakage of fluid, protein and cells into lung airspaces. Degra...

Journal: :IEEE Trans. Geoscience and Remote Sensing 2003
M. Susan Moran Ross Bryant Chandra D. Holifield Stephen A. McElroy

The refined empirical line (REL) approach was used to convert the Earth Observing 1 (EO-1) Advanced Land Imager (ALI) sensor digital number (dn) to surface spectral reflectance ( ). The dn-torelation was derived from a bright target of known reflectance in the image, and the modeled estimates of the image dn at . The mean absolute percent difference ( ) between retrieved from ALI using the REL ...

Journal: :The Netherlands journal of medicine 2009
A Ahmed M Kojicic V Herasevich O Gajic

Acute lung injury (ALI ) and its more severe form, acute respiratory distress syndrome (ARDS ), are important critical care syndromes for which the treatment options are limited once the condition is fully established. Enormous basic and clinical research efforts have led to improvements in supportive treatment, but surprisingly little has been done on the prevention of this devastating syndrom...

Journal: :The European respiratory journal 2006
J D Christie

A cute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), are important public health issues, and both incidence and mortality increase with age [1]. Given that only a moderate percentage of individuals with the same level of exposure develop ALI/ ARDS, it is logical to investigate whether inherent interindivid-ual variation will, in part, determine the risk...

2018
Youzhi Lin Yongqiang Li Xiaohua Hu Zhihui Liu Jun Chen Yulei Lu Juan Liu Sina Liao Yumei Zhang Rong Liang Yan Lin Qian Li Caoyong Liang Chunling Yuan Xiaoli Liao

Currently, the underlying mechanism of oxaliplatin (OXA) induced live injury is unclear. In addition, there is no standard clinical treatment for OXA-induced acute liver injury (ALI). In this study, we established an animal model of OXA-induced ALI, and studied the role of oxidative stress in OXA-induced ALI and the impacts of reduced glutathione (GSH) treatment on OXA-induced ALI. To establish...

2015
Shunying Jin Michael L. Merchant Jeffrey D. Ritzenthaler Kenneth R. McLeish Eleanor D. Lederer Edilson Torres-Gonzalez Mostafa Fraig Michelle T. Barati Alex B. Lentsch Jesse Roman Jon B. Klein Madhavi J. Rane

Immune-complexes play an important role in the inflammatory diseases of the lung. Neutrophil activation mediates immune-complex (IC) deposition-induced acute lung injury (ALI). Components of gamma amino butyric acid (GABA) signaling, including GABA B receptor 2 (GABABR2), GAD65/67 and the GABA transporter, are present in the lungs and in the neutrophils. However, the role of pulmonary GABABR ac...

Journal: :Internal medicine 2007
Tadatomo Kodama Hidekazu Yukioka Takayuki Kato Noboru Kato Fumihiko Hato Seiichi Kitagawa

OBJECTIVE To determine whether the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) associated with systemic inflammatory response syndrome (SIRS) can be predicted by the plasma neutrophil elastase level. PATIENTS AND METHODS Patients were sequentially enrolled after obtaining informed consent. Twenty-three adult patients with SIRS were classified into the...

2012
Jason D. Christie Mark M. Wurfel Rui Feng Grant E. O'Keefe Jonathan Bradfield Lorraine B. Ware David C. Christiani Carolyn S. Calfee Mitchell J. Cohen Michael Matthay Nuala J. Meyer Cecilia Kim Mingyao Li Joshua Akey Kathleen C. Barnes Jonathan Sevransky Paul N. Lanken Addison K. May Richard Aplenc James P. Maloney Hakon Hakonarson

Acute Lung Injury (ALI) is a syndrome with high associated mortality characterized by severe hypoxemia and pulmonary infiltrates in patients with critical illness. We conducted the first investigation to use the genome wide association (GWA) approach to identify putative risk variants for ALI. Genome wide genotyping was performed using the Illumina Human Quad 610 BeadChip. We performed a two-st...

2016
Hsuan-Chung Wu Hsing-Hao Chen Yu-Ren Zhu

We systematically investigated the effects of Al-impurity type on the formation energy, crystal structure, charge density, electronic structure, and optical properties of ZnO by using density functional theory and the Hubbard-U method. Al-related defects, such as those caused by the substitution of Zn and O atoms by Al atoms (Als(Zn) and Als(O), respectively) and the presence of an interstitial...

Journal: :Chest 2012
Rajanigandha Dhokarh Guangxi Li Christopher N Schmickl Rahul Kashyap Jyoti Assudani Andrew H Limper Ognjen Gajic

BACKGROUND A number of drugs have been reported as risk factors for acute lung injury (ALI) and ARDS. However, evidence is largely limited to case reports, and there is a paucity of data on the incidence and outcome of drug-associated ALI (DALI). METHODS Using a population-based retrospective cohort study design, critically ill patients with a diagnosis of ALI were studied. These patients wer...

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