Although initial serum albumin level is highly associated with overall and cardiovascular mortality in peritoneal dialysis (PD) patients, we consider that the dynamic change and trend of albumin after initiation of PD are also essential.We enrolled patients who received PD for more than 3 months from January 1999 to March 2014. We categorized these patients into 2 groups by the difference in se...

Objective: As the coronavirus disease 2019 (COVID-19) pandemic continues, clinical and laboratory predictors of progression to serious lethal types illness are urgently needed. We aimed investigate how well hematologic, biochemical, immunologic biomarkers could distinguish between patients with without severe or fatal COVID-19. Material Methods: This retrospective study was performed in interna...

PURPOSE To compare the abundance and spatial distribution of serum albumin in the mouse and bovine cornea. METHODS Serum albumin from cornea was separated from transketolase by SDS-PAGE (+/-dithiothreitol [DTT]) and identified by peptide sequencing and immunoblot analyses. The fractional content of serum albumin was determined in water-soluble extracts of cornea by imaging analyses after SDS-...

Objective: To study the role of peroxynitrite-modified human serum albumin (nitroxidized-albumin) in rheumatoid arthritis. Methods: Human serum albumin was exposed to peroxynitrite and changes in albumin structure were monitored by UV-visible, fluorescence and circular dichroism spectroscopy, thioflavin T, Congo red binding and attenuated total reflection-Fourier transformed infrared spectrosco...

It is well established that brain blood barrier dysfunction following the onset of seizures may lead to serum albumin extravasation into the brain. However, the effect of albumin extravasation on the development of epilepsy is yet to be fully elucidated. Previous studies have predominantly focused on the effect of albumin absorption by astrocytes; however, the present study investigated the eff...

Sejalan dengan kemajuan teknologi di bidang farmasi, teknik mikroenkapsulasi telah digunakan untuk memperbaiki stabilitas zat aktif. Tujuan: Penelitian ini bertujuan mengetahui apakah bisoprolol dapat mikrokapsul mengggunakan albumin. Metode: bersifat eksperimental memformulasikan albumin sebagai penyalut yang adalah 1:6, 1:4 dan 1:2 berturut-turut Formula I, II III menggunakan metode penguapan...

We tested the hypothesis that an elevation in albumin synthetic rate contributes to increased plasma albumin content during exercise-induced hypervolemia. Albumin synthetic rate was measured in seven healthy subjects at 1-5 and 21-22 h after 72 min of intense (85% peak oxygen consumption rate) intermittent exercise and after 5 h recovery in either upright (Up) or supine (Sup) postures. Deuterat...

Previously we reported that chronic renal failure in rats leads to preferential disaggregation of liver membrane-bound polysomes associated with a decrease in albumin synthesis. To determine whether reduced albumin synthesis results from reduced cellular levels of albumin messenger RNA (mRNA) or some other molecular mechanism, we have employed mRNA-DNA hybridization in conjunction with cell-fre...